ABSTRACT
Hodgsonia heteroclita fruits have been used as traditional drug for antidiabetic in Western Assam, India. The study aimed to investigate antioxidant activity of methanolic fruit extract of H. heteroclita. The antioxidant activity of fruit was determined by employing different In vitro assays such as DPPH•, ABTS•+ radical scavenging capacities and reducing power assay-phosphomolybdenum. The results of the present study revealed that the methanol fruit extract exhibited strong scavenging effect on DPPH (2,2-diphenyl-1picrylhydrazyl) with IC50 =20.98±0.17 than ABTS [2,2´-azino-bis(3-ethylbenzothiazoline-6-sulphonate) with IC50 =28.58±0.42. The reducing power phosphomolybdenum assay showed inhibition with ascorbic acid as standard. Fruit extract exhibit free radical scavenging and reducing properties which might constitute an important source of natural antioxidants. Thus the study indicates that this plant has a potential to be used as an antioxidant and also can be used to prevent diseases directly linked to oxidative stress.
ABSTRACT
Plasma cell leukemia (PCL) is a rare type of plasma cell dyscrasia. It is diagnosed when circulating plasma cells (PC) are more than 20%. We present a case of PCL in a 62-year-old female. Peripheral smear revealed more than 80% atypical vacuolated plasma cells (Mott cells) almost mimicking Burkitt cells of Acute Lymphoid Leukemia-L3 (ALL-L3). Bone marrow aspirate revealed few mature myeloma cells for which a diagnosis of PCL was thought of. Serum electrophoresis showed a positive M-band and X-ray revealed lytic lesions over femur & pelvic bones. A final diagnosis of PCL was given.