ABSTRACT
This was a retrospective analysis of all consecutive breast cancer specimens submitted to the Pathology Department Of Federal Medical Centre, Gombe which renders histopathology services to four states in the North Eastern region of Nigeria. A total of 172 cases of malignant breast tumours were recorded during the 7 years under review. Out of the 172 cases of breast cancers analysed, 7(4%) were in males while the remaining 165(96%) were in females giving a male: female ratio of 1:24. The most common histopathological type of breast cancer found in this study was Invasive Ductal Carcinoma no special type (NST) accounting for 78.8% of cases (Afr J Reprod Health 2011; 15[1]: 107-109)
Subject(s)
Breast Neoplasms , Carcinoma, Ductal, Breast , WomenABSTRACT
Background: Breast cancers tend to be more aggressive in younger patients and some histopathological types like medullary; mucinous and tubular variants have a better prognosis. This study describes the histopathologic pattern and tumour grade of breast carcinoma in younger patients. Methods: This was a retrospective analysis of all consecutive breast cancer specimens submitted to the histopathology department of Federal Medical Centre Gombe during the study period. The data was analyzed with EPI Info 2002 using simple means and percentages. Results: A total of 167 cases of breast carcinoma in 164 females were reviewed with three patients having bilateral disease. The age range of the study population was 22-75 years with a mean age of 44 +/-11.7 years. One hundred and twenty seven patients (76) were aged less than 50 years while the rest were above 50 years. A total of 133 tumours were invasive ductal carcinomas; 107(80.45) of which were in the premenopausal age group and 26(19.55) in post menopausal age. One hundred and six patients (63.5) had low grade tumours (grades 1 and 2) while 61(36.5) had high grade tumours (Grades III and IV tumours). Forty three (70.5) of these high grade tumours were seen in premenopausal age group. Eleven patients had invasive lobular carcinoma of which 4(36.4) were premenopausal while 7(63.6) were post menopausal. Conclusion: It is concluded that younger patients tended to frequently have aggressive and high grade disease