ABSTRACT
Osteosarcoma is a highly malignant bone tumour. It is derived from primitive mesenchymal bone forming cell. Osteosarcoma of the jaw is quite rare. Despite its rarity, the dentist may be the first health professional who observes tumours involving the jaws. As there is a greater variability in clinical, radiological and histopathological findings of jaw osteosarcoma, so there is greater scope for multidisciplinary approach. An early definite diagnosis is must for successful treatment which can save patient’s life and esthetic. This article presents a case of osteosarcoma in medically compromised 17 years old female patient who was misdiagnosed initially and later on present as a huge size of the tumour mass with gross disfigurement than she was treated by multidisciplinary approach of oncosurgeon, medical oncologist and radiation oncologist with appropriate expertise.