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1.
Gulf Journal of Dermatology and Venereology [The]. 1997; 4 (2): 1-9
in English | IMEMR | ID: emr-44698

ABSTRACT

The histopathology of cutaneous leishmaniasis is marked by a T-cell mediated immune response ranging from well-defined epithelioid granuloma formation with few orgnaisms in patients with an intact immune response to a diffuse infiltrate of histiocytes with numerous organisms in patients with a poor immune response. In this respect, there is a similarity to infection by mycobacterium leprae. The tropism of the infectious Leishmania organism, that of the innoculum, and the underlying immune strains of the patient will determine the clinical and histologic findings. Further study into the immunopathology should lead to greater uinderstanding of the pathologic findings and improved treatments. Furthermore, the use of polymerase chain reaction and other methods of verification utilizing immunoperoxidase staining should lead to greater diagnostic confidence


Subject(s)
Leishmaniasis/pathology , Polymerase Chain Reaction/methods
2.
Gulf Journal of Dermatology and Venereology [The]. 1996; 3 (1): 30-31
in English | IMEMR | ID: emr-41026

ABSTRACT

We are reporting a series of 19 patients with 20 nodular basal cell epitheliomas removed by elliptical surgical excision. Histologic examination of the specimens by serial sections in each case revealed a central nodular growth surrounded by a number of small nests of basalioma cells in connection with the lower surface of the epidermis and the infundibular portion of the pilosebaceous structures. The superficial nests extended as far as 5.5 mm distant from the central nodule. The nodular lesion was completely excised in all cases. However, the peripheral nests extended to the line of excision in 13 of the 20 specimens requiring re-excision of the area. The re-excisional specimens were positive for residual superficial nests in six of the 13 cases


Subject(s)
Humans , Male , Female , Carcinoma, Basal Cell/pathology , Histological Techniques
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