Effect of alcohol on serum lipids in diabetics

This report emanated from a three-year study conducted at the Diabetic Outpatient Clinics convened at the Port-of-Spain and Sangre-Grande Hospitals in Trinidad. The diabetic population which participated consisted of 132 men and 245 women of African descent; and 99 men and 163 women of East Indian origin. The mean age was 50 years (ñ13). The effect of alcohol on lipid fractions varied in the races. A lower incidence of ischaemic heart disease was observed among the alcohol consumers when compared to those who abstained

The effect of blood sugar, therapy and blood pressure on lipoprotein profiles of diabetics in Trinidad & Tobago: possible association with ischaemic heart disease

The aim of this investigation was to examine the effects of fasting blood sugar, the type of therapy and blood pressure levels on lipoprotein profiles of diabetics in Trinidad and Tobago, and to determine how these biochemical and physiological risk factors may influence the development of ischaemic heart disease. Seven hundred (700) diabetic patients attending outpatient clinics at Sangre Grande and Port-of Spain General Hospitals were surveyed. The data obtained in this study on the relationship of serum lipids to diabetic control support the hypothesis that poor control of blood sugar is conducive to accelerated atherosclerosis. Hypertensive patients and those maintained on insulin showed a greater predisposition to ischaemic heart disease (IHD) that did non-hypertensives and patients maintained on oral hypoglycaemic agents, respectively

The effect of demographic factors on serum lipids in diabetics of Trinida & Tobago: possible association with ischaemic ischamic heart disease

This study was undertaken in order to investigate the effect of race, sex, weight, activity level and to determine how this could possibly relate to the incidence of ischaemic heart disease (IHD). Seven hundred (700) diabetics attending outpatient clinics at Sangre-Grande and Port-of-Spain hospitals were screened. There were 132 males and 249 females of African descent; 99 males and 163 females of East Indian extract, and 19 males and 38 females of other ethnic origins. The average age of the population studied was 50 years (ñ 15). The results obtained from this study indicate that diabetes mellitus is apparently more common in women that in men, particularly in those women who have borne children, and the incidence rises markedly after menopause. East Indians have higher triglyceride (TG), very low density lipoprotein cholesterol (VLDL-C) and low density lipprotein cholesterol (LDL-C), but lower high density liprotein cholesterol (HDL-c) concentrations than their counterparts of African origin. TG, LDL-C and total serum cholesterol (TC) concentrations are highest in overweight-obese patients while HDL-C concentrations are highester in the lower weight division. The domestic working class, as well as those who were in retirement, have higher TG, LDL-C than members of ther occupational status. The fractions mainly affected by a residental area are TG, HDL-C. Moreover, diabetes mellitus and its consequent impact on lipoprotein homeostasis a greater predilection to IHD, especially among members of the East Indian community