ABSTRACT
Background: Preeclampsia is associated with maternal and neonatal complications. It has been indicated that increased uric acid might have a predictive role on preeclampsia
Objective: We aimed to investigate the relationship between the level of uric acid with maternal and neonatal complications in women with preeclampsia
Materials and Methods: In this cross-sectional study, 160 singleton preeclamptic women at more than 28 wk gestational age were included. Hemoglobin, hematocrit, platelet count, liver and uric acid tests, and maternal and neonatal complications were assessed. The severity of preeclampsia, placental abruption, preterm labor, thrombocytopenia, elevated alanine aminotransferase and aspartate aminotransferase [ALT and AST], HELLP syndrome, eclampsia and required hospitalization in the ICU was considered as the maternal complication. Fetal complications were: small for gestational age [SGA], intrauterine fetal death, hospitalization in the neonatal intensive care unit, and Apgar score <7 at five minutes
Results: Of our participants, 38 women had severe preeclampsia [23.8%]. The mean level of uric acid in women with severe preeclampsia was significantly higher than non-severe preeclampsia [p=0.031], also in those with an abnormal liver test [p=0.009]. The mean level of uric acid in women with preterm delivery was significantly higher than women with term delivery [p=0.0001]. Also, the level of uric acid had no effect on neonatal hospitalization in neonate invasive care unit. Based on logistic regression, the incidence of severe preeclampsia not affected by decreased or increased serum levels of uric acid
Conclusion: With higher level of uric acid in server preeclampsia we can expected more complications such as hepatic dysfunction and preterm delivery. Thus serum uric acid measurement can be helpful marker for severe preeclampsia
ABSTRACT
Educational programs for promotion of mental health in marital life are necessary. Ignorance of target group needs diminishes effectiveness of efforts in educational programs. This research aimed to report and compare mental health educational needs before and after marriage. In a cohort study in 2011, by random stratified sampling 450 males and females were selected. These were participated in pre-marital counseling in Hasheminezhad center in Tehran. A researched-made questionnaire was used to measure rate of mental health educational needs with 5 degree-Likert scale before and six months after marriage. Data were analyzed by Independent t-test, paired t-test and Prioritization was done by calculating mean rank. A P-value less than 0.05 have been considered as significant different. "How to keep romance alive in marital life" topics was the first priority in both before and after marriage. Rates of mental health educational needs in both stages were more than average [3 degree]. After marriage rate of needs was increased but it was not significant. Women in both stages report more rate of educational needs than men but this difference wasn't significant. Designing mental health promotion educational programs based on people needs are necessary and these programs should be performed in different stages of life