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OBJECTIVE:To explore the clinical efficacy and safety of oxymatrine membrane,rhEGF gel respectively com-bined with Yunnan baiyao for postoperative cervical wound after LEEP. METHODS:300 patients with cervical intraepithelial neo-plasia(CIN)Ⅱ and Ⅲ were divided into group A,B,C(100 cases in each group)based on CIN grading and stratification and random sampling in each stratification. After conventional LEEP,patients in group A were cleaned the wound by 0.9% Sodium chloride injection,spraying Yunnan baiyao powder,once only after surgery;patients in group B were additionally given recombi-nant human epidermal growth factor (rhEGF) on the basis of group A,once every week after surgery,for 3 weeks;patients in group C were additionally given oxymatrine membrane on the basis of group A,1 tablet every evening after surgery,for 2 weeks. Postoperative bleeding,bleeding duration,rebleeding and duration after postoperative bleeding stopped,postoperative drainage du-ration,the incidence of adverse reactions in 3 groups were observed. RESULTS:The patients of postoperative bleeding,bleeding time ≥7 d and rebleeding after stopping bleeding in group B were significantly lower than group A;the incidence of bleeding time ≥7 d in group C was significantly lower than group A,the proporition of postoperative drainage duration for less than 7 d was significantly higher than group A,for 8-13 d was significantly less than group A;early wound healing rate in group B and group C were significantly better than group A,with statistical significances (P0.05),and there were no obvious adverse reactions in 3 groups. CONCLU-SIONS:Oxymatrine membrane and rhEGF gel respectively combined with Yunnan baiyao have better healing than Yunnan baiyao alone,do not increase the incidence of adverse reactions,while there is no significant difference in oxymatrine membrane and rhEGF gel.
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Objective To investigate the effect of Xuebi-jing injection on the change of the serum high-sensitivity C-reactive protein (hs-CRP) in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods 86 patients with AECOPD were enrolled in this study, who was randomly divided into a control group (43 cases)and a treatment group (43 cases). Both treatment group and control group were given conventional therapy. On this basis, Xuebi-jing injection was added to the treatment group. Hs-CRP, blood gas analysis, blood cell count and severity of illness score (acute physiological and chronic health evaluation Ⅱ, APACHE Ⅱ) were monitored before and 5 days after treatment. Results There was no obvious difference of hs-CRP levels between two groups before treatment. Hs-CRP was decreased in both groups after the treatment, while the treatment group showed an obvious decrease compared with the control group (t＝5.3302,P＜0.01). Blood gas analysis, blood cecount, APACHE Ⅱ scores were improved after the treatment in both groups, while the improvement in treatment group showed obvious difference than the control group (t＝13.5089、26.3077 、13.4053,P＜0.01). Conclusion The conventional therapy plus Xuebi-jing injectiong for AECOPD can improve serum hs-CRP levels and improve the efficacy of AECOPD .
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Objective Evaluate the diagnostic value of PET/CT in the preoperative advanced gastric carcinoma comparing with mult;-slice spiral computed tomography. Methods Thirty-nine advanced gastric carcinoma patients taking PET/CT and abstract 40 advanced gastric carcinoma patients performing MSCT before operation,were done the TNM staging, and the Results were compared with the operation histopathology. Results For diagnosing primary lesions, regional lymph nodes, N3 lymph nodes ,PET/CT was accurate in 92.3% , 66.7% and 100.0%.Instead, MSCT was accurate in 82.0% , 50.0% and 62.5%. Conclusions (1) PET/CT and MSCT have high accuracy in diagnosing primary lesions and regional lymph nodes. But for detecting the N3 lymph nodes and distant metastasis, PET/CT has higher accuracy than MSCT. PET/CT combining abdominoscopy may decrease or avoid exploratory laparotomy.