ABSTRACT
OBJECTIVES: To assess the efficacy of a home made energy dense weaning food, containing 110-130 kcal (26-30kJ) per 100 ml on prevention of growth faltering during infancy. METHODOLOGY: Infants attending four child health welfare clinics in the Medical Officer of Health (Ragama) area were recruited at the age of 4 months. The intervention group received a specially designed hand blender, recipe and advice to prepare a weaning food. The control group received weaning foods without any intervention. They were followed up monthly up to the age of 12 months. RESULTS: 152 infants completed the study (83 from intervention group). The infants in the intervention group gained significantly more weight than the control group (intervention group 2.43 +/- 0.72 kg, control group 2.02 +/-0.62 kg, p = 0.0002). Both groups showed a drop in the Z score for mean weight for age during the study period but this was less marked in the intervention group. CONCLUSIONS: A high energy density home made complementary food was effective in improving the weight gain of infants during the weaning period.
Subject(s)
Body Mass Index , Body Weight , Female , Humans , Infant , Infant Food , Infant Nutritional Physiological Phenomena , Infant, Newborn , Male , Nutrition Surveys , Surveys and Questionnaires , Sri Lanka , Weight GainSubject(s)
Adolescent , Autoantibodies/analysis , Autoantigens/metabolism , Autoimmunity , Chemoprevention , Child , Female , Goiter, Endemic/enzymology , Humans , Hypothyroidism/enzymology , Iodide Peroxidase/metabolism , Iodine/deficiency , Iron-Binding Proteins/metabolism , National Health Programs , Prevalence , Sodium Chloride, Dietary/standards , Sri Lanka/epidemiology , Thyroglobulin/metabolismABSTRACT
OBJECTIVES: To determine knowledge about four genetic disorders (Down's syndrome (DS), haemophilia (haem), spinal muscular atrophy type 1 (SMA1) and Huntington's disease (HD)), attitudes towards counselling, acceptability of prenatal diagnosis and termination of pregnancies affected with these conditions. DESIGN: Questionnaire survey of a cohort of medical students and newly qualified doctors. SETTING: Faculty of Medicine, University of Ruhuna. RESULTS: 227 completed questionnaires (111 fourth year and 86 final year students, and 30 demonstrators) were analysed. Awareness of DS and haem, was higher than of SMA1 and HD, and was highest among the demonstrators. Over 80% of the cohort would not counsel directively about future pregnancies and would discuss the diseases with the family or at risk individuals. Prenatal diagnosis was found acceptable for DS, haem and SMA1 by a majority of the cohort. Attitudes to termination of affected pregnancies varied, 88%, 77%, 55% and 36% finding it acceptable for DS, SMA1, haem, and HD respectively, provided legal terminations were available and termination was requested by parents. CONCLUSIONS: This cohort of students and doctors appear to accept the principles of clinical genetics involving non-directive counselling, prenatal diagnosis and in some disorders, termination of pregnancy.
Subject(s)
Adult , Cohort Studies , Genetic Counseling , Health Knowledge, Attitudes, Practice , Humans , Physicians/psychology , Prenatal Diagnosis , Surveys and Questionnaires , Students, Medical/psychologyABSTRACT
Since 1955, numerous cases of Cronkhite-Canada syndrome have been reported in adults. We present here the first Asian report of the infantile Cronkhite-Canada syndrome. While the prognosis in adults is variable, in children, it is less optimistic.
Subject(s)
Adult , Colon/pathology , Developing Countries , Diagnosis, Differential , Diseases in Twins , Female , Humans , Infant , Intestinal Polyps/diagnosis , Rectum/pathology , Sri LankaSubject(s)
Adolescent , Adoption/legislation & jurisprudence , Child , Child Abuse, Sexual , Female , Humans , Sri LankaSubject(s)
Cesarean Section , Female , Humans , Infant, Newborn , Male , Muscular Diseases/genetics , Neck Muscles/abnormalities , Neoplasms/genetics , Pregnancy , Torticollis/etiologySubject(s)
Child , Child Abuse/legislation & jurisprudence , Child, Preschool , Developing Countries , Female , Humans , Male , Sri LankaABSTRACT
Illegal adoption procedures may lead to many medical and legal problems. Two case reports are used to illustrate some of these. The present Sri Lankan law in relation to these aspects is discussed.
Subject(s)
Adoption/legislation & jurisprudence , Humans , Male , Sri LankaABSTRACT
A six week old baby girl from a closed Malay community in Hambantota presented with gradually increasing oedema since two weeks of age. She was oedematous, with gross non selective proteinuria, hypoproteinaemia and hypercholesterolaemaia. Congenital nephrotic syndrome is extremely rare and has not been reported previously in Sri Lanka.
Subject(s)
Female , Humans , Infant , Nephrotic Syndrome/congenitalSubject(s)
Adolescent , Adult , Female , Humans , Lipoid Proteinosis of Urbach and Wiethe/diagnosis , Male , Sri LankaABSTRACT
OBJECTIVE: To determine some factors associated with infant mortality. DESIGN: Descriptive study. SETTING: Galle district in Sri Lanka. SUBJECTS: 350 infant deaths of singleton births. MEASUREMENTS: Association between variables. RESULTS: Neonatal:post-neonatal death ratio was 3.2:1, and 62.3% (218) were early neonatal deaths. First day deaths comprised 28.6% (100); 67.8% (237) died at the Teaching Hospital. A high incidence (65.7%) of low birthweight (LBW) was noted. Mean birthweights of neonates and post-neonates were 1925 +/- 729 and 2520 +/- 620 gram respectively, and the difference between means was statistically significant (p < 0.001). LBW and related disorders were the major cause of death in 44% (154) of the total sample, and in 55.8% (149) of neonates. Infections were the commonest cause (55.8%) of death in post-neonates. Pediatric clinical assessment to differentiate small-for-dates (SFD) was not recorded in 90.3%. Statistically significant associations were found between the period of death (neonatal and post-neonatal) and the following variables: period of gestation (p < 0.001); birthweight (p < 0.001) and cause of death (p < 0.001). CONCLUSIONS: There was a high incidence of neonatal deaths and a high proportion of early neonatal deaths. About one-third of deaths occurred on the first day of life. Incidence of LBW was high. The major cause of death was LBW and related disorders in the total sample and in neonates. Assessment of SFD was not carried out in the vast majority of infants.
Subject(s)
Cause of Death , Female , Humans , Incidence , Infant , Infant Mortality , Infant, Low Birth Weight , Infant, Newborn , Infant, Small for Gestational Age , Male , Sri Lanka/epidemiologyABSTRACT
We report three patients with fulminant hepatic failure following sepsis managed by exchange transfusion. The literature on the role of infection in the pathogenesis of fulminant liver failure and of exchange transfusions in its management is reviewed.