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China Journal of Chinese Materia Medica ; (24): 934-936, 2012.
Article in Chinese | WPRIM | ID: wpr-356041

ABSTRACT

<p><b>OBJECTIVE</b>To apply the membrane separation process in the concentration process of Chuanxiong Chatiao granules and to lay the foundation for its industrialized application.</p><p><b>METHOD</b>The type of membrane, the optimal pressure, the optimal temperature and the optimal detergent were selected by the single factor method. A comparative study was conducted between qualities of extracts from Chuanxiong Chatiao granules by new and traditional processes.</p><p><b>RESULT</b>The type of membrane was determined to be SMN-130A2350054. The optimal pressure was 1.7 MPa. The optimal temperature was 36 degrees C and the optimal detergent was 1% sodium polyphosphate. The qualities of extracts from Chuanxiong Chatiao granules by new and traditional processes showed no difference.</p><p><b>CONCLUSION</b>The selected membrane separation process can effectively achieve concentration and save energy. The extracts from Chuanxiong Chatiao granules by the new process show no difference with traditional processes. Therefore, it provides basis for the industrialized application of Chuanxiong Chatiao granules.</p>


Subject(s)
Drugs, Chinese Herbal , Chemistry , Technology, Pharmaceutical , Methods
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