1.
Rev. méd. Chile
;
123(3): 293-7, mar. 1995. tab
Article
in Spanish
| LILACS
| ID: lil-151183
ABSTRACT
The presence of aminoglycoside modifying enzyme (AMEs) has been investigated by an agar diffusion method, in 344 strains of aminoglycoside-resistant Gram negative bacilli isolated in different Chilean hospitals. Most of the strains exhibited a combination of enzymatic mechanism of resistance, but 2 acetylatting (AAC(3)II and AAC(6')I) and one phosphorylating (APH(3')I) enzymes were mechanism detected in the strains. A significant increase in the frequency of strains producing AAC(6')I), possibly due to wide use of amikacin, has been found when results were compared with those of a report published in 1985
Subject(s)
Humans , Drug Resistance, Microbial , Gram-Negative Bacteria/drug effects , Anti-Bacterial Agents/pharmacology , Communicable Diseases/enzymology , Gram-Negative Bacteria/enzymology , Enzyme Activation
2.
Rev. méd. Chile
;
118(5): 548-54, mayo 1990. tab
Article
in Spanish
| LILACS
| ID: lil-87688