ABSTRACT
ObjectiveTo assess cost-effectiveness of pramipexole and levodopa/benseraside in the hospitalized Parkinson's disease (PD) patient.Methods81 PD patients were divided into group A(levodopa/benserazide group) and group B( pramipexole combined with levodopa/benserazide group) according to different pharmacotherapy.The curative effects and costs of hospitalized PD patients were evaluated.The curative effects were evaluated by unified Parkinson's disease rating scale (UPDRS).ResultsThere were 44 patients in group A and 37 patients in group B.Although B group in drug costs and treatment costs were increased more significantly than A group ( P ＜0.01),but declined markedly UPDRS after treatment ( P ＜ 0.05 ) than A group.Pramipexole can be applied in all kinds of Hoehn and Yahr states in PD.ConclusionAlthough the combination of pramipexole would increase drug costs and treatment costs,but could improve the clinical symptoms of PD,and can be applied to different stages of PD.It should be individualized recommendation in the Parkinson's patients.
ABSTRACT
Objective To study the changes of blood glucose concentration of acute cerebrovas-culor disease with different character and various degrees,and its significance and the fluence on prognosis. Methods The blood glucose datas of 196 cases of acute cenebrovscular diseade without DM were retrospectively analysed and compared with the clinical statulo. Results There were 107 cases of cerebral infarction and 89 cases of cerebral hemorrhage in 196 cases of acute cerebrovaocular disease. The blood glucose rose 42% in the cerebral infarction group and 45% in the cerebral hemorrhage group;Based on the location and the range of the lesion, the concentration rising of blood glucose existed significant difference between the group of thalamus and internal capsule and the group of ganglion basal and external capsule(P