Laparoscopic totalextraperitoneal inguinal hernia repair 302 clinical analysis / 中国医师进修杂志

Objective To explore surgical options and clinical outcome of preperitoneal hernia repair (TAPP) and totally ext raperitoneal hernia repair (TEP) in inguinal hernia repair.Methods The clinical data of 302 patients underwent laparoscopic herniorrhaphy were retrospectively analyzed.Results None of patient s was changed to open operation.The TAPP and TEP outcome measures:the unilateral hernia surgery time from (31.2 ± 8.3) min and (55.3 ± 15.2) min,bilateral hernia surgery time was (46.2 ± 11.2)min and (80.2 ± 23.2) min; blood loss was (6.4 ± 2.0) ml and (7.2 ± 1.6) ml,bed activity for the first was (16.0 ± 1.8) h and (16.0 ± 1.5) h,hospital stay was (3.0 ±0.6) d and (3.1 ±0.8) d.Conclusions Laparoscope herniorrhaphy is safe due to lower recurrence and complications.It also has the advantages of slight pain and rapid recovery.

A study of hepatocyte apoptosis and its gene expression in patients with liver cirrhosis and portal hypertension / 中国普通外科杂志

Objective To study the relationship of hepatocyte apoptosis and gene expression of liver cirrhosis and primary hepatic carcinoma. Methods Specimens of liver tissue from patients with liver cirrhosis and portal hypertension and normal subjects were examined by transmission electron microscope to detect apoptotic cells and primary cancer gene expression. Results The number of apoptotic cells and the apoptotic index of cirrhotic liver tissue was higher than that of normal subjects.Immunostaining of bcl 2,c myc,c fos was negative in normal liver tissue ,but was over expressed in cirrhosis. Conclusions Hepatocyte apoptosis plays a certain role in the development of hepatic cirrhosis. The oncogenes bcl 2,c myc,c fos take part in the regulation of hepatocyte apoptosis .

Early endoscopic therapy for acute biliary pancreatitis / 中国普通外科杂志

Objective To evaluate the therapeutic effect of duodenoscopy in the early treatment of acute biliary pancreatitis (ABP).Methods Twenty ABP cases admitted from Oct.2000 to Mar.2004 received emergent endoscopic retrograde cholongiopancreatography (ERCP), sphincterotomy (EST) plus endoscopic lithotomy and endoscope naso-biliary drainage (ENBD).Other 16 cases were treated with conservative therapy or open surgery.Results Successful rate of endoscopic management was 95%.There were no severe complications nor mortality in this group.The duration of symptoms and hospitalization in endoscopy group were significantly shorter than control group ( P