ABSTRACT
Objective To evaluate the efficacy of endoscopic ultrasonography(EUS)guided implantation of 5-FU seeds for progressive gastric cancer.Methods A total of 23 patients with progressive gastric cancer and outflow obstruction were enrolled into the study.During the endoscopy procedure, 45-60 5-FU seeds were implanted into the tumors with guidance of EUS, with an average dose of 100 mg.Volumes of tumor were examined with 3D-EUS before and after the treatment.Results A total of 33 procedures of 5-FU implantation were performed.By measurements of 3D-EUS, the numbers of patients with complete respons, partial response, no change, progressive disease were 1, 15, 6 and 1, respectively.In terms of outflow obstruction improvement, significant effect, obvious effect and average effect were achieved in 6, 7 and 9 patients, respectively, with an overall response rate at 91.4%.Conclusion EUS-guided 5-FU seed implantation in progressive gastric cancer is safe,reliable and effective with few complications.3D-EUS may be a new method to evaluate curative effect.
ABSTRACT
Objective To explore the value of transanal placement of ileus decompression tube in left colon carcinoma with obstruction. Methods Data of 35 patients with complete malignant colon obstruction, who underwent placement of ileus decompression tube by colonoscopy and fluoroscopy with guidewire from January 2007 to December 2009, were retrospectively studied. Results Tube placement was successfully performed with one procedure in all 35 patients. Phase Ⅰ surgery was achieved in 34 patients at 7 - 10 days after decompression. The tube desquamated in 1 case 2 days after the placement, and was replaced successfully, and the patient received phase Ⅰ resection 8 days after. No perforation or other complications occurred in any cases. Conclusion Placement of ileus decompression tube, assisted with colonoscopy and fluoroscopy, simple and safe, can immediately relieve the symptoms of intestinal obstruction, decrease the risk of emergency operation and help to avoid colonostomy and phase Ⅱ radical operation.