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1.
Journal of Biomedical Engineering ; (6): 697-700, 2012.
Article in Chinese | WPRIM | ID: wpr-271706

ABSTRACT

The hemodynamic characteristics of abdominal arterial bifurcation, such as blood flowing velocity vector, the shear stress at the vessel wall were calculated, studied and compared using the newly-induced boundary element method in this study. It was analysed why the atherosclerosis is asymmetrical at the bifurcation of abdominal arterial. The hemodynamic causes of production and development of the atherosclerotic were reasonabley explained by the shear stress calculation results of left and right common iliac branch vessel walls before and after the lesions. It is shown that the distribution of blood flowing velocity vector, the shear stress at the vessel wall are asymmetrical because of the asymmetrical geometry at the bifurcation of abdominal arterial, so that the shear stress of inner wall is higher than outside. The inner wall shear stress of right common iliac is higher than left. Blood velocity and shear stress increase at the atherosclerotic lesion because the blood vessel becomes narrower, and the blood velocity and shear stress decrease at the downstream of the lesion. It was also shown that the hemodynamic characteristics played a great important role in the occurrence and development of the atherosclerosis diseases at the bifurcation of abdominal arterial. Because of the increase of the shear stress, the atherosclerotic plaque surface will be damaged, leading to tissue hyperplasia. It will be lead to blood cell coacervation that the blood velocity and shear stress decrease at the atherosclerotic plaque downstream.


Subject(s)
Humans , Aorta, Abdominal , Pathology , Atherosclerosis , Pathology , Blood Flow Velocity , Physiology , Finite Element Analysis , Hemodynamics , Shear Strength , Physiology , Stress, Mechanical
2.
Journal of Biomedical Engineering ; (6): 814-817, 2008.
Article in Chinese | WPRIM | ID: wpr-342737

ABSTRACT

In this paper a kind of arterial bifurcation vessel's hemodynamic characteristics are studied with the boundary element method, and the blood flowing velocity vector distributions are calculated when there is pathologic change in the branch vessel wall and when there is no pathologic change. The shear stress value at the lateral wall and that at the medial wall are compared when there is pathologic change in the main branch vessel wall and when there is no pathologic change. Moreover, the flow field distribution and the pressure on the particle surface are calculated, when there is flow-round particle at the place of bifurcation. The move tendency of the particle is judged, and the possible factors in causing atherosclerosis are analyzed.


Subject(s)
Humans , Arteries , Physiology , Atherosclerosis , Blood Flow Velocity , Computer Simulation , Hemodynamics , Physiology , Models, Cardiovascular , Stress, Mechanical
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