ABSTRACT
A total of 184 men with uncomplicated gonococcal urethritis were treated with a single oral dose of rifampicin 900 mg and erythromycin stearate 1 gm. The cure rate on day 3 was 95.1%, 175 were cured and 9 failed (4.9%). Of all the Neisseria gonorrhoeae isolated, 86 were PPNG (46.7%). There was no difference in failure rate among patients with PPNG or with non-PPNG. With the exception of self-limited gastrointestinal disturbance, side effects were minimal. The value of this combination for the treatment of uncomplicated gonococcal urethritis in men is promising and deserves further study.
Subject(s)
Adolescent , Adult , Aged , Ampicillin/therapeutic use , Clinical Trials as Topic , Costs and Cost Analysis , Drug Therapy, Combination , Erythromycin/analogs & derivatives , Gonorrhea/drug therapy , Humans , Male , Middle Aged , Neisseria gonorrhoeae/drug effects , Penicillin Resistance , Probenecid/therapeutic use , Rifampin/therapeutic use , Thailand , Urethritis/drug therapyABSTRACT
Result of rubella haemagglutination inhibition antibody test on 300 Thai women of childbearing age in upper socioeconomic group showed that 25% were susceptible to rubella. The high frequency of susceptibility in this group of women would be of considerable public health problem, should rubella become epidemic again. The introduction of immunization against rubella in this group of women was also discussed.