ABSTRACT
Despite extensive research in understanding toxic effects of monocrotophos, some uncertainty exists. The results showed a decrease in SOD activity both in smoker and non-smoker exposed groups when compared to the control group in the present study. The mean SOD activity in non-smoker control group was 1263±7.22 and the same has decreased to 496.0±9.123 in the non-smoker exposed group. Similarly a decrease in SOD activity was observed in smoker exposed group. While SOD activity in control group is 1258.3±12.79 it has decreased to 496.0±9.12 in the smokers exposed to monocrotophos pesticide. The results showed a decrease in GPX activity both in smoker and nonsmoker exposed groups when compared to the control group. The mean GPX activity in non-smoker control group was 20.62±4.14 and the same has decreased to10.75 ±2.87 in the non-smoker exposed group.
ABSTRACT
Occupationally exposed monocrotophos pesticide sprayers revealed various health complications like hyper tension, chronic bronchitis, cardiovascular problems, headache, eye irritation, cold, sinus problems, asthma, backache, fatigue, skin allergy, joint pains and acidity. There was a significant decrease in antioxidant enzyme activity in exposed group when compared to control group. Significant increase was seen in the activity of Glutathione-Stransferase in long term exposure to monocrotophos pesticide sprayers. Present study is an attempt to explore the status of usage of monocrotophos in Ramayanpet Village of Medak district in Andhra Pradesh State of India.