ABSTRACT
In a prospective analysis of ocular fireworks injuries over three consecutive years (1997 to 1999) during the Indian festival of Diwali, 42 patients presented with various types of fireworks-related ocular injuries. Twenty two (52%) patients had to be admitted for the management of their ocular injuries.
Subject(s)
Adolescent , Adult , Blast Injuries/epidemiology , Child , Child, Preschool , Explosions/statistics & numerical data , Eye Injuries/epidemiology , Humans , Incidence , India/epidemiology , Prospective Studies , Visual Acuity/physiologyABSTRACT
A 15 year old boy presented with diminution in vision of both eyes, diabetes insipidus and hypopituitarism. MRI was suggestive of a large suprasellar and retrosellar craniopharyngioma with stretching of the optic chiasma. Histopathological findings on the first surgical specimen were interpreted as a craniopharyngioma. He was reoperated on account of clinical deterioration and increase in tumour size. Histological examination this time revealed derivatives of all three germ cell lineages along with areas of embryonal carcinoma, and yolk sac tumour besides squamous cysts, establishing the diagnosis of malignant mixed germ cell tumour. Serum and CSF were strongly positive for alpha foetoproteins.
Subject(s)
Adolescent , Craniopharyngioma/pathology , Diagnosis, Differential , Germinoma/pathology , Humans , Magnetic Resonance Imaging , Male , Mixed Tumor, Malignant/pathology , Optic Chiasm/pathology , Pituitary Neoplasms/pathology , alpha-Fetoproteins/analysisABSTRACT
Three cases of damage to the optic nerves and chiasma following pituitary irradiation with Co60 teletherapy are described. All of them presented with progressive visual impairment months following irradiation and simulated recurrence of the tumour. CT scan was also not helpful in differentiating radionecrosis from tumour recurrence. On exploration the optic nerves and chiasma appeared discoloured and scarred. One case, who also had diffuse radionecrosis of brain parenchyma, died. No satisfactory therapy is currently available for this grave complication but proper safeguards can prevent it.