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Rev. Soc. Bras. Med. Trop ; 40(2): 197-203, mar.-abr. 2007. tab
Article in Portuguese | LILACS | ID: lil-452622

ABSTRACT

O estudo descreve os sintomas referidos por portadores da forma indeterminada da doença de Chagas crônica e avalia sua associação com alterações da motilidade esofágica. Manometria do esôfago foi realizada em 50 pacientes, medindo-se a extensão e a pressão do esfíncter inferior do esôfago, o peristaltismo e a amplitude de contração do corpo esofágico. Oito (16 por cento) pacientes apresentaram relaxamento parcial do esfíncter inferior, 13 (26 por cento) apresentaram aperistalse parcial e 20 (40 por cento) apresentaram hipocontratilidade no esôfago distal. Sintomas digestivos altos foram referidos por 24 (48 por cento) pacientes, sendo mais freqüentes a pirose, a regurgitação e o desconforto intermitente à deglutição. Esses sintomas foram referidos por 17 (51,5 por cento) de 33 pacientes com alterações motoras do esôfago e por 7 (41,2 por cento) de 17 pacientes com manometria normal, diferença essa não estatisticamente significante (p=0,69). Esses achados sugerem que portadores da FCI apresentam sintomas inespecíficos do trato digestivo superior que podem dificultar a sua classificação com base apenas no exame clínico e radiológico, e que é alta a freqüência de portadores desta forma que apresentam distúrbios motores do esôfago.


This study describes the symptoms reported by patients with the indeterminate form of chronic Chagas disease and evaluates associations between these symptoms and alterations in esophageal motility. Esophageal manometry was performed on 50 patients, with measurements of the length and pressure of the lower esophageal sphincter, peristaltism and the amplitude of contractions of the esophageal body. Eight (16 percent) patients presented partial relaxation of the lower sphincter, 13 (26 percent) presented partial lack of peristalsis and 20 (40 percent) presented hypocontractility of the distal esophagus. Upper digestive symptoms were reported by 24 (48 percent) patients, and the most frequent of these were heartburn, regurgitation and intermittent discomfort when swallowing. Such symptoms were reported by 17 (51.5 percent) of the 33 patients with esophageal motor disorders and by 7 (41.2 percent) of the 17 patients with normal manometry, which was not a statistically significant difference (p=0.69). These findings suggest that patients with the indeterminate form of Chagas disease present nonspecific symptoms in the upper digestive tract that may make it difficult to classify the disease solely on the basis of radiological and clinical examination. Furthermore, a high proportion of patients with this form present esophageal motor disorders.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Chagas Disease/complications , Esophageal Motility Disorders/etiology , Chronic Disease , Esophagoscopy , Manometry
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