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Background : Reproductive Tract Infection (RTI) due to poor hygiene caused by faecal Bacteria or viruses which goes into the vaginal canal during and after defecation is not only damaging to the reproductive organ, but also causes indirect or direct impact on Socio-economic status of the patient and their family as well. Objective : This study highlights the importance of faecal hygiene in preventing damage to the reproductive tract and curbing the impact on social and economic problems in patients and their families. Materials and Methods : This study was conducted at GICE Nursing Home, Kalyani, Nadia, WB, between April 2016 and March, 2022. During this period, 11,872 cases were reported at GICE Nursing Home of which 10,000 cases were selected. Discussion : It was interesting to observe that those who wipe from back to front or vice versa are more likely suffering from Vaginitis (85%), Cervicitis (92%), Endometritis (55%), PID (60%), UTI (70%) and Tubal Block (17%) as compared to those who used Hand shower (10%) or Tissue Paper (9%). This is an indication that proper faecal hygiene can prevent damage to the reproductive system. Further analysis revealed that the inability to pay for medical expenses created a Socio-economic crisis among family members. Conclusion : It is concluded from this study that maintenance of proper faecal hygiene by women in Rural, Urban and Industrial areas, can not only help with prolonged illnesses but also prevent financial losses. As a result, Guardians, Teachers, Health Care Providers and Local Government should conduct outreach programs to teach the importance of faecal hygiene at home, in Schools, Colleges, Public health institutions and so on, etc
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Purpose: Our study aimed to evaluate the utility of the anterior segment morphometry for objectively assessing anterior segment architectural changes of corneal clouding in the mucopolysaccharidoses (MPS) cohort and to investigate whether these measurements correlate with the slit?lamp findings on the cornea and early diagnosis of glaucoma. Methods: This retrospective study involved 70 eyes of 35 children with cloudy cornea due to MPS variants. Anterior segment architectural alterations were measured using anterior segment imaging and biometry in MPS children and compared with controls. Results: Mean age of the cohort at the time of assessment was 7.9 ± 4.5 years. Males constituted two?thirds of the cohort. Variants of MPS with cloudy cornea were as follows: Type I (62%), Type IV (11%), and Type VI (22%). Morphometric measurements were available in 22 eyes of 11 MPS children and an age?matched healthy control group. There were significant differences between MPS cohort and controls in refraction in Diopters (5.03 ± 0.39 and 0.01 ± 0.04; P < 0.0001), axial length (AXL) in mm (21.39 ± 0.28 and 23.04 ± 0.28; P = 0.0002), average keratometry in Diopters (40.67 ± 0.44 and 42.83 ± 0.44; P < 0.0001), anterior chamber depth (ACD) in mm (2.92 ± 0.07 and 3.65 ± 0.07; P < 0.0001), and intraocular pressure (IOP) in mmHg (25.2 ± 2.0 and 14.1 ± 2.3; P = 0.0003). Secondary glaucoma was observed in 28% of the MPS cohort. Conclusion: The anterior segment morphometry in the cloudy cornea due to MPS provides an objective measurement of anterior segment architectural changes, thus diagnosing early?onset secondary glaucoma. These findings highlight that cloudy cornea due to MPS variants merits close monitoring throughout life
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Background: Usually for lower abdomen and lower limb short surgical procedures, spinal anaesthesia is a reliable and safe anaesthesia technique.2-chloroprocaine (2-CP) is an amino-ester local anaesthetic with a very short half-life. Adjuvants are required with short acting local anaesthetic for spinal anaesthesia to prolong analgesia. Aims and Objectives: The present study was conducted to analyse the effect of 2-CP alone and with fentanyl combination in spinal anaesthesia for short surgical procedures in terms of onset of block, adequacy of anaesthesia, analgesia and recovery. Materials and Methods: The study was conducted in our hospital in 60 patients undergoing lower abdomen and lower limb short surgical procedures under spinal anaesthesia with either 2-CP or 2-CP and fentanyl (group I or group II) after randomisation into two groups. Spinal anaesthesia characteristics of sensory and motor block, duration of analgesia were noted and appropriate statistical analysis was performed. Results: The onset of sensory and motor block was faster in group II[5.00 ± 3.19 vs 7.156 ± 3.38 min. (p= 0.0138) and 8.03 ± 5.65 vs 11.03 ± 3.97 min. (p= 0.021)] than in group I, and duration of effective analgesia was prolonged in group II (147.63 ± 40.71 vs 130.40 ± 50.85 min with p value of 0.0002)as compared to group I. Eleven patients in group I required analgesic supplementation in the intraoperative period. Conclusion: The patients undergoing short surgical procedures of lower abdomen and lower limb under spinal anaesthesia with short acting local anaesthetic 2-CP with fentanyl as an additive provides rapid onset of sensory and motor block and prolonged duration of analgesia.
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Introduction: One of the essential components for maintaining health is having proper and adequate nutrition. The absence of this might affect majorly the physical domain of health, especially in under‑five children as it is the age of development. The present study was conducted among the tribal under‑five children in a tribal predominant block, Mohammad Bazar in Birbhum District of West Bengal to find out their nutritional status, along with the estimation of prevalence of anemia among them; and the association, if any, between the nutritional status of the study population with their demographic, socioeconomic, and environmental characteristics. Materials and Methods: This community‑based cross‑sectional study was conducted among 378 tribal under‑five children residing in 21 villages of Mohammad Bazar Block during September 2018–August 2020 using Lot Quality Assurance Sampling (LQAS) technique. A predesigned, pretested schedule was used to collect necessary information regarding background characteristics. Anthropometric measurements (height and weight) and biochemical estimation (hemoglobin level in blood) were done to evaluate nutritional status. Ethical permission was obtained from Institutional Ethics Committee, Burdwan Medical College. Data were analyzed using the Statistical Package for the Social Sciences, version 20. Results: The present study showed that 31.0% of under‑five children were underweight, 16.6% severely underweight, 31.5% stunted, 17.2% severely stunted, 21.7% wasted, and 7.7% severely wasted. Nearly one‑third of the study participants were suffering from anemia and most of them (91.5%) had mild anemia. As per LQAS, none of the villages had acceptable nutritional status as far as the weight for age and height for age was concerned. Conclusions:This research unveiled that the undernutrition in various forms still persists among the tribal under‑five children. Rigorous implementation of various schemes, missions, and programs by both state and Central Government are the need of the hour to overcome this downhearted situation
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Hydroxamic acids are directly related with cancer and its progression. Long term exposure with inflammatory responses, dysplasia develops which leads to cancer. Metastasis of cancer and expression of transient potential receptor ankyrin-1 are known to cause severe pain. Here, we explored the possibility of developing newer hydroxamic acid derivatives as anti-inflammatory and analgesic agent. Animals were administered with 100 mg/kg dose of the synthesized imidazolyl triazolo hydroxamic acid derivatives (FP1-FP12) and 50 mg/kg dose of standard diclofenac sodium. Carrageenan induced rat paw edema and Eddy’s hot plate methods were considered for anti-inflammatory and analgesic activities. Among all the synthesized molecules, FP10 and FP4 were the most effective anti-inflammatory and analgesic agent, respectively. The activity profile of remaining molecules as anti-inflammatory agents was as follows: FP4>FP9> FP8> FP2 and as analgesic activity profile was FP10>FP3>FP8 >FP11 >FP2 > FP12. Presence of ethyl- benzyl and furan groups in linker portion of the structure minimized both the anti-inflammatory and analgesic activities. Results have shown that compounds with electron releasing groups considerably enhance both anti-inflammatory and analgesic activities.
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Midgut malrotation is a congenital anomaly seen usually in childhood. Its presentation as an acute intestinal obstruction is extremely rare in adults usually identified intra operatively. A high index of suspicion is always required when dealing with any case of acute intestinal obstruction. We report a case of young adult who presented with symptoms of acute intestinal obstruction and was diagnosed intra-operatively as cecal volvulus with impending perforation caused by midgut malrotation. Malrotation of the intestinal tract is seen due to aberrant embryology. The presentation of intestinal malrotation in adults is very rare. Contrast enhanced Computed tomography (CT) can show the abnormal anatomy clearly. Anomalies like midgut malrotation can present as an operative dilemma and awareness regarding these conditions can help surgeons deal with these conditions.
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Background: Chronic kidney disease (CKD) is one of the vital health problems worldwide leading to increased global morbidity and mortality. Thyroid dysfunction including hypothyroidism, hyperthyroidism and non-thyroidal illness has been reported in CKD patients. This study was conducted to determine the prevalence of subclinical and overt hypothyroidism among chronic kidney disease patients. This study also tried to correlate thyroid function abnormalities with severity of renal failure.Method: In this observational and cross sectional study, 100 patients of CKD who were admitted in Department of Medicine, Rajendra institute of medical sciences, Ranchi were studied for thyroid function abnormalities. Result: This study found that glomerular filtration rate (GFR) is positively correlated with serum T3 and T4 level (i.e. with decreasing renal function both T3 and T4 levels decreased). Serum creatinine levels were negatively correlated with serum T3 and T4 level.Conclusions: From this study it was established that CKD is associated with thyroid dysfunction characterized by low serum fT3 and fT4 with high TSH in some cases.
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Milking behaviour of dairy cows has serious impacts on their production efficiency. A number of genetic and environmental factors controls and influences milking behaviour of dairy cow. The aim of present study was to investigate the influence of housing comfort on expressivity of milking behaviours of cows in parlour, milk yield and compositions. Forty Jersey crossbred cows of similar production levels were selected and divided into 2 groups based on age, production and parity. Subsequently, cows were kept in two different types of loose house; each containing 20 animals. Two types of housing patterns were compared - (i) Traditional shed (T0) and (ii) Thermo-comfortable shed (T1). Impact of housing comfort significantly transformed the expressions of dairy cows behaviour even in milking parlour. Milking temperament scores and stepping during milking were significantly lower in cows kept in T1 compared to that of T0. Cows of thermo-comfortable shed showed more docile, calm and less nervous behaviour than those kept in traditional shed. Housing patterns significantly influenced daily milk yield (kg) being 2.86% more in T1 as compared to T0. Similarly milk compositions were better and significantly higher in T1 group of cows than that of T0. It was concluded that staying comfort of living by resignificantly modulated the expression of dairy cows behaviours even in milking parlour, demonstrated favourable milking temperament, reduced nervousness, enhanced milk yield and showed better milk compositions in Jersey crossbred cows
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Alteration during far off dry period feeding management was done to see its effect on body weight and body measurements of Jersey cross bred cows. This study was conducted on 14 healthy dairy animals which were separated into two comparable groups on the basis of almost similar age groups, parity, body weight, and body condition score. Statistically analyzed data revealed that there was significantly higher (p<0.01) tail head thickness in overall dry period and at calving in control group animals than treatment group animals. Significantly higher (p<0.01) overall abdominal girth after 4 months of lactation was found in control group animals as compared to treatment group animals. Significantly higher (p<0.01) body length during overall dry period and at calving was noticed in control group animals. Non significant (p>0.05) difference was reported in body weight and heart girth among control and treatment group animals. The coefficients of correlation indicated high and significant (P<0.01) correlation among body condition score, tail head thickness, body length, heart girth, abdominal girth in this study. It can be concluded that alteration of feeding management practices during far-off dry period does not significantly change body weight during dry period and post partum period but can lead to significant difference in some body measurements of Jersey crossbred cows at tropical lower Gangetic region. Correlation of parameters suggested that the larger body sized animal of same breed may produce more milk.
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Background: Being both highly prevalent public health problems in India, anemia in pregnancy (AIP) is hypothesized as a potential risk factor for low birth weight (LBW) baby as pregnancy outcome. In this context, this study was conducted among pregnant mothers registered in last 2 years under Bhatar block of Purba Bardhaman district, West Bengal. Objectives of this study were to assess the relationship of LBW babies with maternal anemia in antenatal period and also with background characteristics and pregnancy related factors.Methods: A retrospective cohort analysis was conducted among postnatal mothers who were registered during their pregnancy in sub-centers of this block during a reference period from April’15th - March’17th. The study subjects were identified from the records of each sub-centre and further categorized into two groups: Exposed (anemic) - Hb <11 gm% in any antenatal visits and Non-exposed(non-anemic) - Hb ≥11 gm% in all antenatal visits. Sample size of 988 for each group was calculated. From each sub-centre’s antenatal record 26 subjects for each group were selected by simple random sampling. Data collected with predesigned pretested schedule and data analyzed using Microsoft Excel and SPSS 20. Logistic regression was performed to establish association.Results: Overall incidence of LBW was 8.1%; in anemic, non-anemic group incidence were 10.5%, 5.7% respectively. AIP had relative risk 1.85 (1.36-2.54) over LBW. On multivariable logistic regression, LBW was significantly associated with AIP (2.11, 1.51-2.95), multi-parity (0.63, 0.44-0.9), inadequate ANC visits (2.7, 1.75-4.15) and female gender (1.64, 1.19-2.27).Conclusions: Anemia in pregnancy significantly increases risks of LBW which also strongly associated with female new-born, primi-parity, and incomplete ANC visits
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Background: Iodine deficiency disorder is one of the preventable public health diseases in India. Prevalence of goiter is also still prevalence at sub-Himalayan region of West Bengal. Study was conducted to assess prevalence of goiter among school students between 6 and 12 years age, to find out urinary excretion of iodine and iodine content in salt sample and to recommend for consuming iodized salt.Methods: We conducted the study among the school students aged 6 to 12 years during the month of June 2018 in Purba Medinipur district, West Bengal, India. Multistage cluster sampling method was conducted for selecting the study population. Clinical examination was done by medical officer to detect goiters. Salt and urine samples were taken from the selected students and were sent to State Iodine Monitoring Laboratory, Kolkata for examination of iodine content in household salt samples and urine samples.Results: Total 2821 students were examined for survey. Over all prevalence of goiter was 3.75% (109/2821). Girls had more prevalence 4.63% than boys 3.18%. Average urinary iodine excretion (UIE) level is 184.74% in 30 clusters of 339 urine samples. Only 5.60% showed UIE level ≤100 microgram/liter. Total 541 household salt samples were tested for iodine and average iodine content was 22.85%. Among them 91.5% (495) had iodine ≥15 ppm indicating adequate iodine contents in salt samples.Conclusions:Purba Medinipur may be considered a non-endemic district. We recommended continuing use of iodized salt.
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Mucinous adenocarcinoma of the renal pelvis is a rare tumor constituting < 1 % of all tumors involving the kidney. We are presenting the case report of a 45-years-old female who presented with pus discharging sinus from the scar of previous surgery after 2 years of initial surgery. On CECT, the left kidney showed heterogeneous space-occupying lesion of size 10x6 cm. The patient underwent cytoreductive excision of mass followed by adjuvant radiotherapy. The patient was doing well and asymptomatic till 8 months of follow-up but after 8 months, she presented with recurrence and died after another 4 months. To our knowledge, none of the previous papers reported discharging sinus as a mode of presentation for mucinous adenocarcinoma of the kidney. The outcome of the patient with relevant literature is being discussed here
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Background: There is a paradigm shift in the social values towards the elderly people due to urbanization and higher educational linked migration. Consequently, problems like loneliness, lack of emotional support, economic insecurities are faced by the elderly population. The objectives of the study were to assess the socio-economic dimensions and to examine the morbidity and mortality patterns of elderly persons in the study area.Methods: A cross- sectional study was conducted among 536 elderly persons from May to August 2019 in an urban area of Udaipur. A pre-structured and pre-tested questionnaire was used to collect information on socio-demographic details, morbidity profile and socio-economic problems of elderly persons. The data was analyzed using class frequencies, ‘t’ test for equality of gender difference in mortality ages and Chi-square test for association of age class with morbidity.Results: A majority of study subjects were females (52.05%). There was significant difference in proportions of elderly male and female persons across their educational levels. The chi-square test for association of age classes with number of health problems revealed significant association. About 56.34% of 536 elderly people were leading an unsatisfactory life.Conclusions: The major morbidities included arthritis, hypertension, diabetes, cataract, dental problems, cardiovascular problems etc. Financial problems were more severe among elderly. The availability of trained paramedical professionals for home care and day care units and legal bindings on family members for safety and security of elderly person can be effective measures to overcome the problems being faced by them.
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Background: Previous studies have suggested that the clinical features of vesicoureteral reflux in infants differ from those of older children with regard to the male-to-female ratio and severity of renal parenchymal damage. Aim of the study is to know the profile and pattern of primary vesicoureteral reflux in subjects seeking care at a tertiary care teaching centre of southern India.Methods: This was a hospital based study, conducted at the Department of Paediatrics, Kasturba Medical College located at Manipal during August 2004 - August 2012 over a period of 8 years. All the children in the age group of 1 month to 18 years with Vesicoureteral Reflux, who presented to the study centre during study period, were included in the study.Results: Majority (78.5%) presented before 5 years, youngest age at presentation was 1 month and oldest at 14 year 8 months. Among 93 children studied, 65 were males and 28 were females with male to female ratio of 2.3. The commonest presenting complaint was fever (58%), followed by recurrent Urinary tract infection (UTI) (40.8%), dysuria 32 (34.4%) and reports of documented UTI was available in 23 (24.7%) cases. Four children had hypertension at presentation. Thirteen of them had associated posterior urethral valve. Neurogenic bladder was present in 3 children, 2 had associated Anorectal malformation and one had meningomyelocele.Conclusions: Majority of vesicoureteral reflux cases presented before 5 years of age. There was a preponderance of males. Majority had grade IV and V reflux. The mean age at presentation of vesicoureteral reflux was 3.6 years. The commonest presenting complaint was fever, followed by recurrent UTI.
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Background: Hygienic practices performed by the rural women during menstrual cycle is often remain unsatisfactory, resulting adverse health outcomes and poor productivity. Assessment of the practices among different population groups as well as different geographical locations thus has been a priority issue. The objective of this study is to assess the menstrual hygiene practices among the village women attending a Primary Health Centre of Sipahijala district, Tripura.Methods: The study was conducted among 141 village women of reproductive age group (15-49 years), visited Madhupur primary health centre, Sipahijala district, Tripura for some other health conditions. Unwilling individuals were excluded from the study. Data were collected using a pre-designed pre tested schedule by interviewing the participants for basic socio-demographic variables as well as questions related to hygienic practices during menstrual period. Data were analysed using IBM SPSS version 20 and presented using principles of descriptive statistics. Ethical clearance was obtained from Institutional Ethics Committee, Tripura Medical College.Results: Majority of the study subjects belonged to 21-30 years of age group (49.3%). Cloth was the major absorbent material (44.0%) followed by sanitary napkin (36.2%). 47.5% of the study subjects reused the material. Only 2.1% of the study subjects changed the material less than 2 times/day. More than 90% of the study subjects clean their private parts regularly. 66.0% of the study subjects disposed the material in dustbin.Conclusions: Majority of the participants were performing satisfactory menstrual hygienic practices. However, large scale analytical studies will be helpful to draw a definite conclusion about influence of sociodemographic factors on menstrual hygiene practices.
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Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosis of squamous cell carcinoma of the renal pelvis is usually unsuspected due to the rarity and inconclusive clinical and radiological features. The insidious onset of symptom and lack of any pathognomonic sign leads to delay in the diagnosis and subsequent treatment, resulting in grave prognosis for these patients. Here, we present a case of incidentally detected renal squamous cell carcinoma in a 71-year-old male with a staghorn calculus and Xanthogranulomatous pyelonephritis. The patient was treated with radical nephrectomy
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Background: Effects of percutaneous nephrolithotomy (PCNL) operation on ipsilateral renal function are widely known but functional changes in opposite kidney are limited. Authors have conducted this study to evaluate the impact of PCNL operation on the contralateral side during early post-operative period.Methods: From 1st November 2016 to 30th September 2018, those patients presented with unilateral renal stone disease were enrolled. After exclusion they were subjected to PCNL operation under general anaesthesia. Along with preoperative period, 99 m Tc DTPA renal scan is repeated at 3rd and 14th post-operative period.Results: Out of 121 patients enrolled we included 96 patients after exclusion. They are divided into 3 age groups, 19-32, 33-47 and 48-60 years. The mean GFR at pre-operative, post-operative day-3 and 14 of normal kidney in these 3 age groups are 47.32, 47.63 and 42.32 ml/min, 44.29, 45.78 and 40.63 ml/min and 47.10, 48.47 and 41.01 ml/min respectively. At post op day-3 there are reduction of mean GFR in all age groups but statistically not significant (p >0.05). At post-operative day-14 GFR improved towards the pre-op value but the change is also not significant (p >0.05).Conclusions: There are reduction of GFR of contralateral normal kidney following PCNL operation in early post-operative period. So, along with operated kidney normal kidney also showed decrease GFR. It is better to avoid further trauma in post PCNL patient like avoidance of using nephrotoxic medication, contrast agents, ESWL, etc. This study can guide us to avoid further trauma of any kidney.
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Background: The level of personal hygiene has a strong bearing on preventive capacity for many diseases and hence the assessment of its level assumes great significance. The school being a strong base for hygienic practices, the present study aimed to assess the level of personal hygiene and its associated factors as well as its effect on morbidity level of school children in a rural belt of southern Rajasthan.Methods: The cross-sectional study was conducted among 250 students studying in classes VIII to XII in 3 different schools of southern Rajasthan from November 2018 to February 2019.The data was obtained by interview method using pretested questionnaire which included socio-demographic factors, the hygienic practices and occurrence of diseases as dichotomous questions. The association of the attributes was tested through Chi-square test, correlation and regression techniques.Results: Only 22% students scored above 75% and were categorized as good practioners of personal hygiene. The age of students, parents literacy, and household income were significantly associated with personal hygiene. The common morbidities like head lice and dental caries were found gender sensitive in the study area. The negative association between disease score and personal hygiene score implied that the disease burden of children can be minimized with higher personal hygiene practices.Conclusions: Systematic efforts to sensitize school children and parents about importance of personal hygiene, improvement in parental literacy coupled with economic empowerment of rural families can help to enhance the status of personal hygiene of students and thereby drastic reduction in their disease burden.
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Background: The rationale of determining the percentage ofanalgesics used in postoperative period is to determine the realutilization of opioid sparing effect of nonsteroidal antiinflammatory drugs and the concept of multimodal analgesia.Objectives: To determine the cost of opioids consumptionbecause the opioids are expensive.Methods: Total 541 patients were selected to find out thetypes of analgesics are being used in the postoperative eperiod irrespective of the types of operation and anaesthesia,premedication by analgesics and intraoperative analgesicsused or not. Patients were divided into several age groups.Results: In the existing prospective cross sectional study it isviewed that combination of intramuscular injection of pethidineand nonsteroidal anti-inflammatory drugs (either in suppositoryform or intravenous or intramuscular route) have the highestpercentage in postoperative pain relief.
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The incidence of foreign body insertion in urethra was rare, but there has been a gradual increment in such cases nowadays.. The most common cause is to get sexual gratification. The management of these cases is individualized according to size, type, and location. Here we present a unique case report of earphone in the urinary bladder. A 17-year old male was admitted to the hospital with earphone inserted in his urinary bladder. The boy was operated for the removal of the broken end of the earphone. Such cases are common and needs proper attention and care which should be coupled with psychiatric consultation.