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OBJECTIVE:To study the value of bronchoalveolar lavage fluid(BALF) bacteria culture and drug sensitivity test in the hospital-acquired pneumonia(HAP) therapy.METHODS:The bacteria types in BALF samples and drug sensitivity test in 516 HAP cases were analyzed retrospectively.RESULTS:The positive rate of BALF culture was 46.9% with the main pathogenic bacteria of Candida albicans,Acinetobacter baumannii,Pseudomonas aeruginosa,Klebsiella pneumoniae.Of total nosocomial pneumonia,single bacteria infection accounted for 58.9% and mixed infection 41.1%.Candida had no drug resistance against 5-fluorocytosine,amphotericin B.Extended spectrum ? lactamase was found in 75.9% of Escherichia coli and 35.7% of Klebsiella pneumoniae with severe drug resistance.CONCLUSIONS:BALF bacteria culture and drug sensitivity test can provide reference for rational use of drug in the clinic.
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OBJECTIVE:To observe the effect of Buflomedil Injection plus backwards traction and functional exercises on the hemorheology of patients with vertebral artery type of cervical spondylosis. METHODS:Sixty patients with vertebral artery type of cervical spondylosis were treated with 0.2 g Buflomedil Injection (diluted with 500 mL 0.9% Sodium Chloride Solution or 5% Glucose Solution,q.d by slow iv gtt for two courses of treatment with 7 days defined as 1 course) plus backwards traction and functional exercises. Patients' hemorheologic parameters including blood viscosity high shear rate,blood viscosity low shear rate,plasma viscosity,erythrocyte aggregation index,erythrocyte rigidity index,hematocrit,and fibrinogen etc were detected before and after treatment. RESULTS:Before treatment,all the hemorheologic parameters were significantly higher than the reference values of healthy adults(P
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OBJECTIVE To explore the relationship between Ureaplasma urealytium(Uu),Mycoplasma hominis(Mh),and Chlamydia trachomatis(Ct) with infertilitas feminis.The drug sensitivity can offer evidence for rational usage to improve the cure rate.METHODS Of 320 cases of infertility womenthe,primary infertility accounted for 132 cases and the secondary infertility for 188 cases.Other 120 cases of normal women were chosen as control.Secretion samples were used to detect Uu,Mh,Ct,and drug sensitivity.RESULTS The rate of Uu,Ct,Uu+Ct,Uu+Mh in infertility group was significant higher than control group(P0.05);minocycline doxycycline,josamycin and erythromycin cyclocarbonte were sensitive to Uu+Mh;drug resistance rate was higher in Uu+Mh infection, multidrug resistance was very serious.CONCLUSIONS Uu,Mh and Ct infections are the major factors to infertilitas feminis.The detection of Uu,Mh and Ct is good for diagneosis.
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OBJECTIVE:To study the composition of pathogenic bacteria and drug resistance in biliary tract infection for clinicians' reference about rational application of antibiotics. METHODS:Bacteria culture and drug susceptibility analysis were performed for the bile samples of 235 cases. RESULTS:The detection rate of pathogenic bacteria in bile was 61.7%,with gram-negative bacilli representing 59.3%,gram-positive bacilli 38.9% and Candida mycoderma 1.8%. With regard to constituent ratios of the bacteria,leading the first 4 places were enterococci(37.7%),Escherichia coli(29.3%),Klebsiella(18.6%) and Pseudomonas aeruginosa(5.4%). The main gram-negative bacilli were sensitive to imipenem and amikacin; whereas Enterococci were sensitive to vancomycin,amphemycin,ampicillin,penicillin and high concentration of gentamicin. ESBLs-producing Escherichia coli and Klebsiella totaled 30 strains,and the ESBLs-producing rate was 37.5%. CONCLUSION:Bile bacteria culture and drug resistance analysis serve as reference for clinical rational use of antibiotics.