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ABSTRACT Objective: To identify the obesity diagnosis with the highest association with physical frailty associated with sarcopenia EWGSOP II (sarcopenic obesity). Subjects and methods: We performed a cross-sectional analysis of 371 community-dwelling older adults. Appendicular skeletal lean mass and total body fat (TBF) were assessed using dual-energy x-ray absorptiometry, and physical frailty was defined using Fried's criteria. The phenotypes were identified according to the presence of sarcopenia by EWGSOP II and obesity, which was diagnosed using two concepts: BMI obesity (BMI ≥ 30 kg/m2) and TBF obesity (percentage of TBF ≥ 35% for women and ≥ 25% for men). Finally, the association of each group with physical frailty was evaluated. Results: The mean age was 78.15 ± 7.22 years. Sarcopenia EWGSOP II was diagnosed in 19.8% (n = 73), body mass index obesity was identified in 21.8% (n = 81), TBF obesity was identified in 67.7% (n = 251), and physical frailty was identified in 38.5% (n = 142). In a regression analysis for frailty, sarcopenic TBF obesity presented an odds ratio of 6.88 (95% confidence interval 2.60-18.24; p < 0.001). Conclusion: In older Brazilian adults, sarcopenic obesity diagnosed by TBF obesity has a robust association with frailty and is independent of body mass index.
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HISTÓRICO: Apesar dos esforços que vêm sendo realizados mais recentemente, a falta de córneas para transplantes ainda é uma realidade no Brasil, principalmente em algumas regiões. O Banco de Olhos do Hospital São Paulo tem como objetivo garantir a qualidade e conservação dos tecidos oculares humanos para disponibilizá-los para transplantes. A qualidade do tecido encontra-se diretamente ligada a todos os processos realizados pela equipe do banco de olhos, a partir da seleção dos doadores. OBJETIVO: Conhecer o perfil dos doadores de córneas do Banco de Olhos do Hospital São Paulo num período de dez anos. MÉTODOS: Estudo retrospectivo de fichas de doadores, no período de janeiro de 1996 a dezembro de 2005. RESULTADOS: Chegaram ao Banco de Olhos do Hospital São Paulo 3.624 córneas. A idade média dos doadores foi de 56,8 anos. A faixa etária com maior doação foi de 70-79 anos. A causa mortis mais freqüente foi doença cardiovascular, seguida por neoplasias, doenças respiratórias e trauma. O tempo "enucleação" foi em média de 3,8 horas e o tempo "preservação" foi em média de 3,6 horas. A maioria dos tecidos foi preservada em meios Optisol GS®. Os doadores jovens tiveram maior proporção de córneas consideradas de qualidade "Excelente" ou "Boa". CONCLUSÃO: Ao longo do período estudado de 10 anos, houve tendência de redução no recebimento de tecidos de outros bancos de olhos e progressivo aumento na captação e preservação de tecidos pela equipe do próprio Banco, com redução significativa no tempo de preservação dos tecidos. Os doadores foram, na maioria, do sexo masculino e as doenças cardiovasculares lideraram as causas de óbito. Apesar da maioria das córneas serem provenientes de doadores acima de 60 anos, o maior percentual de aproveitamento de córneas para transplantes ópticos foi de doadores jovens.
BACKGROUND: Despite all efforts towards the improvement of the eye bank system, the shortage of corneal tissue for transplant is still an important issue in Brazil. The Hospital São Paulo Eye Bank aims to provide high-quality ocular tissues for surgery starting with rigorous selection of donors. PURPOSE: To investigate the characteristics of cornea donors to the Hospital São Paulo Eye Bank during a 10-year period. METHODS: Retrospective analysis of Hospital São Paulo Eye Bank records from January 1996 to December 2005. RESULTADS: 3,624 corneas were evaluated by the Hospital São Paulo Eye Bank during this 10-year period. Mean age of donors was 56.8 years the highest proportion being in the 70-79 years age category. The most common cause of death was cardiovascular disease followed by cancer and trauma. Mean "enucleation" and "preservation" times were 3.8 and 3.6 hours, respectively. The number of corneas received by our eye bank from other eye banks decreased substantially whereas the number of corneas harvested by the Hospital São Paulo Eye Bank staff increased. Optisol GS® were the most utilized preservation media and a high proportion of corneas classified as "Excellent" or "Good" came from young donors. CONCLUSIONS: In a period of 10 years, there was a decreasing trend in the number of donated corneas provided by other eye banks to the Hospital São Paulo Eye Bank and an increase in the number of corneas harvested and processed by the Hospital São Paulo Eye Bank staff with a significant reduction of preservation time. Most donors were male and the main cause of death was cardiovascular disease. Although a great proportion of donated corneas came from older donors, the majority of corneas used for optical transplants came from younger ones.