Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Language
Year range
1.
Braz. j. oral sci ; 12(3): 205-211, July-Sept. 2013. ilus, graf, tab
Article in English | LILACS | ID: lil-701307

ABSTRACT

AIM: This experimental study investigated the association between masticatory hypofunction and mandibular morphological dimensions and internal bone characteristics. METHODS: Twentyfour 21-day-old male Wistar rats were randomly divided into two groups, according to the diet consistency. The control group (CG) was fed a solid diet (pellets) and the experimental group (EG) received a powdered diet during 50 days. All animals were euthanized and their mandibles removed and processed for histomorphometric analysis. A calibrated examiner performed linear and angular measurements (mandibular body length and height, mandibular lengths, ramus depth and height, mandibular base depth, mandibular head and gonial angle) on photographs, estimated bone density in the mandibular ramus region on digital radiographs and assessed the area of cortical and trabecular bone tissue in the second molar region, in 5-µm-thick serial cuts stained with Cason's Trichrome. Measurements for the study groups were compared using Mann-Whitney test (α=0.05). larvae to induce experimental candidiasis, and after 24 hours, the survival rate was assessed. RESULTS: some of the macroscopic dimensions evaluated on photographs were significantly smaller in EG compared to CG, specifically mandibular ramus height (10.77 mm vs. 11.11 mm, p=0.0375), mandibular body length (21.67 mm vs. 22.36 mm, p=0.0165) and height (4.24 mm vs. 4.54 mm, p=0.0016), as well as mandibular base depth (1.24 mm vs. 1.47 mm, p=0.0325). The relative mineral bone density was significantly decreased in EG (1.04) compared to CG (1.25), p<0.001. Rats in the EG also presented smaller trabecular and cortical bone area (2.36 mm²) than those in CG (3.16 mm²), p<0.001. CONCLUSIONS: Based on the above-mentioned measurements, it may be concluded that masticatory hypofunction induced by a powdered diet affected mandibular morphology and was associated with significantly reduced bone content.


Subject(s)
Rats , Bone Density , Bone Development , Diet , Mastication , Mandible/anatomy & histology
SELECTION OF CITATIONS
SEARCH DETAIL