ABSTRACT
Background: Japanese Encephalitis (JE) is common in the plains and mountainous areas in Asia \u2013 Pacific. Japanese encephalitis vaccine shows effectiveness in protecting children from JE in some countries such as Japan and Korea. Objective: To evaluate the efficacy of Japanese Encephalitis (JE) vaccination in Thai Binh province during 2003-2007. Subject and Method: Prospective, retrospective and sero-epidemiological methods were carried out on 329 samples collected from viral encephalitis patients and tested by JE MAC-ELISA, the positive average was 41.6% (137/329). Result: It had dramatically dropped from 85.2% in 2003 to 8.5 % in 2007 related to the rate of JE vaccination for children from 1 to 5 years old increasing from 49 % in 2003 to 77 % in 2007. Most of JE confirmed cases were un-vaccinated. Conclusion: JE etiology cause viral encephalitis in children in Thai Binh province was reduced thanks to JE vaccination in EPI program for 1 to 5 year old children. But more than 96% (131/136) of viral encephalitis in 15 years old upward was unknown etiology, the need for further study of the etiology cause viral encephalitis in adults.
Subject(s)
Encephalitis, Japanese , VaccinesABSTRACT
Background: Acute Respiratory Infection (ARI) is a common disease in developing countries. Morbidity and mortality of ARI are high, especially among children under 15 years old. Objectives: To describe socio-graphic factors, seasonal patterns, risky areas and determine the morbidity and mortality rates of acute respiratory infections in Thai Binh province. Subjects and method: This retrospective study reviewed the medical records of 4,585 hospital admitted patients who were diagnosed with ARI including upper and lower respiratory infections such as sore throat, pharyngitis, bronchitis, pneumonia and bronchitis-pneumonia at 8 district hospitals and 1 provincial hospital in Thai Binh province during 2002-2005. The selected medical records were based on the available check list and two standard screening tests. Results:Morbidity and mortality of ARI in Thai Binh province were 61.6 and 0.52, respectively. ARI mainly occurred among children under 5 years old, of which the highest mortality was among those under 12 months of age. Male children were at higher risk of acquiring ARI, but less prone to death than female. Occupation did not significantly associate with the risk of ARI. The morbidity increased sharply during inter-season, e.g. March and October. Thai Binh city, Kien Xuong and Tien Hai district were reported with the highest morbidity in accompany of the high mortality as consequences. Conclusion: The prevention and control methods were recommended to annually focus on the male children aged less than 5 years old during March and October in Thai Binh city, Kien Xuong and Tien Hai district.