ABSTRACT
Background: Induction of labour is the artificial initiation of labour before its spontaneous onset for the purpose of achieving vaginal delivery of the feto-placental unit. It is a common obstetric procedure which is indicated when the benefits to mother or fetus outweigh the benefits of continuing the pregnancy. Most common indication for induction is postdated pregnancy.Methods: Longitudinal Study carried out in department of obstetrics and gynaecology, RIMS, Imphal, Manipur, conducted for duration of two calendar years, with effect from January 2021 in 168 primigravidas who had reached full term or late term pregnancy admitted in ante-natal ward of RIMS, Obstetrics and Gynaecology department.Results: Study was conducted on 168 pregnant women, most of the participants belonged to the age group of 18-34 years (77.9%). Vaginal delivery was the most common mode of delivery (64.8%). Most of the babies (72%) delivered were having birth weight of between 2.5 kg to 3.9 kg. PPH and uterine hyperstimulation are comparatively more in the late term pregnancy as compared to full term pregnancy. Meconium-stained liquor was slightly more in late term pregnancy group as compared to full term pregnancy. Babies delivered by full term pregnant women were having better APGAR score in 1 minute and 5 minutes than the babies delivered by late term pregnancy.Conclusions: Late term Pregnancy is comparatively common in low socio-economic group. The CS rate is comparatively high in Late term pregnancy as compared to Full Term Pregnancy. Poor APGAR score is highly associated with Late term Pregnancy outcome.
ABSTRACT
Background: Pregnant women with underlying heart disease are at increased risk for adverse maternal, obstetric, and neonatal outcomes. One can successfully treat the majority of these incidents if detected early by accurate individual risk assessment and careful follow-up. The aim and objectives of this study were to compare the foeto-maternal outcome in pregnancy with and without heart diseases with period of gestation >32 weeks.Methods: This study was carried out in a tertiary care teaching hospital of Imphal, the capital city of Manipur, using a standard-questionnaires among patients admitted. Data was analysed using SPSS 21.0 with statistical significance set at p<0.05.Results: Study was conducted on 112 pregnant women. The prevalence of heart disease was higher (71.4%) among the primiparous women. Highest occurrence of heart disease (66.1%) was seen in the housewife group. There was increased incidence of pre-term deliveries among pregnant women with heart disease (26.8%). Caesarean section (62.5%) and maternal complications (42.9%) were found to be higher among the pregnant women with heart disease. The incidence of NICU admission of babies was higher among mothers with heart disease (17.9%) compare to 5.4% in mothers without heart disease.Conclusions: Early detection by accurate individual risk assessment and careful follow-up are key to improving outcomes.
ABSTRACT
Aims: To evaluate the level of lipid peroxidation (by measuring malondialdehyde) and endogenous antioxidant enzyme (glutathione peroxidase) in acute myocardial infarction. Study Design: Cross sectional study. Place and Duration of Study: Department of Biochemistry in collaboration with Department of Medicine, Regional Institute of Medical Sciences (RIMS), Imphal, Manipur, India between November 2010 to April 2012. Methodology: Fifty patients (32 male, 18 female) between the age group of 18-90 years suffering from acute myocardial infarction either attending emergency department, out patients department or admitted in intensive care coronary unit (ICCU) RIMS, within 6 hours from the complaint of chest pain were included in the study. Another thirty age and sex matched healthy individuals (18 male and 12 female) were taken as controls. Glutathione peroxidase (GPx) and malondialdehyde (MDA) levels were estimated by Beckman DU 640 spectrophotometer using commercially available kit. The data was analysed using SPSS version 16. Results: The plasma malondialdehyde mean level (4.02±0.72 μmol/L in males and 3.77±0.58 μmol/L in females) was significantly high in the AMI patients compared to the control group (1.34±0.22 μmol/L in males and 1.30±0.26 μmol/L in females) however the glutathione peroxidase mean level (23.3±4.2 u/gHb in males and 23.0±3.6 u/gHb in females) was significantly reduced in AMI patients than the controls group (29.68±1.4 u/gHb in males and 29.57±1.0 u/gHb in females). Conclusion: In conclusion AMI patients have increased oxidative stress and a compromised antioxidant defense system. Therefore, it is recommended that the management strategy for the patients of AMI should include specific antioxidant supplementation along with lowering of lipid peroxidation.