Impact of Diet on Colorectal Cancer Progression and Prevention: From Nutrients to Neoplasms / 대한소화기학회지

Colorectal cancer (CRC), one of the most common cancers worldwide, continues to increase in incidence and mortality rates. This trend is closely linked to changes in dietary habits, which are major risk factors for colorectal cancer. The increase in the incidence of CRC in countries previously considered low-risk and with low socioeconomic status is most likely due to lifestyle and dietary changes. Understanding the influence of dietary factors on the onset of colorectal cancer is essential for prevention and treatment. This review explores the complex interplay between dietary factors and colorectal cancer, focusing on the key nutrients and dietary habits that influence disease onset and progression. The impact of diet on colorectal microbiota and the influence of diet on early-onset colorectal cancer are also reviewed, reviewing recent research on how dietary interventions affect the treatment and recurrence of colorectal cancer. Finally, the future research directions for developing and applying effective dietary intervention strategies are discussed.

The Anticollagenase Effect of Serum in Alkali-burned Cornea in Rabbit

The possible role of collagenase in the development of corneal ulcers has been intensively studied and collagenase inhibitors have been successfully used to control some corneal ulcers. They are cysteine, EDTA, proteoglycan, serum, and medroxyprogesteron, However, most of them are limited in clinical use because of their toxicity and instability except serum, which is not toxic to the host. We carried out an experiment with serum upon alkali-burned rabbit cornea. Serum has potent anticollagenase effect, and prevents corneal ulceration.

A Case of Complicated Microphthelmos

Complicated microphthalmos can be diagnosed when a reduction in global dimension is combined with other ocular anomalies. These include corneal opacities or staphylomas, cataract, aniridia, corectopia, persistance of pupillary membrane or the tunica vasculosa lentis and hyaloid vessel, thickening or ossification of the choroid and various retinal anomalies. Such a deformity is frequently bereditary, and the transmission may be either as an autosomal dominant or recessive or as a sex linked recessive character. A 10-day-old female infant was found to have unilateral microphthalmos with microcornea, corneal opacity, and aphakia.