Progress in Solid-state Nanopore-based Analysis Technology / 分析化学

Nanopore technique is a low-cost tool for single-molecule level analysis without the need of label or amplification. The solid nanopores have been widely used in many fields such as chemistry and life sciences due to their advantages such as high stability, good tolerability, controllable size, and easy for modification. The solid nanopores commonly used in recent years are fabricated using two types of materials: membrane and tube. The membrane materials include silicon nitride, two-dimensional materials, aluminium oxide, and polymer membranes. The tube materials mainly include glass capillary and carbon nanotube. This review summarizes and prospects the research progress of different solid nanopores.

An analysis on current situation and influencing factors of osteoporosis among elderly residents in Lujiazui Community / 预防医学

Objective To explore the prevalence and the influencing factors of osteoporosis among elderly residents in Lujiazui Community and to provide the reference for the prevention of osteoporosis.Methods The cluster sampling was used to select 1956 community residents aged 65 and above for investigation, which was performed with the questionnaire, physical examination and bone mineral density detection. Logistic regression analysis was applied to analyze the influencing factors of osteoporosis. Results The prevalence rate of osteoporosis of 1576 respondents was 35.41%. The prevalence rate in females (46.89%) was higher than males (16.47%) (P<0.01), Logistic regression analysis showed that weight (OR=0.05-0.22), central obesity (OR=5.19, 95%CI: 2.60-1.38), exercise (OR=0.12-0.43), diet (OR=0.34-0.38), drink (ORusual=4.19、 ORdaily=2.86) were the main influencing factors in males.Weight (OR=0.33-0.37), exercise (OR=0.34-0.57), diet (OR=0.25-0.59), diabetes history (OR=1.45, 95%CI: 1.09-1.92), hypertension history (OR=1.39, 95%CI: 1.07-1.82) were the main influencing factors in females. Conclusion The prevalence rate of osteoporosis of residents aged 65 and above in Lujiazui Community was 35.41% , with higher rate in females. Weight control, more exercise and non-vegitarian diets could lower the risk of osteoporosis .