ABSTRACT
Objective To investigate the clinical value of the variety of serum levels of soL-CXCL16 and NT-proBNP peripercutaneous coronary intervention(PCI) in patients with acute myocardial infarction (AMI).Methods A total of 77 cases received PCI were selected to research group.And the contemporaneous 30 healthy persons were chosen to control group.The serum levels of soL-CXCL16,NT-proBNP and cTnT were detected by ELISA.The relationships of soL-CXCL16 and NT-proBNP to cTnT were detected by Pearson linear correlation analysis.Results Compared to pre-PCI,the serum levels of CXCL16 were rising to the peak point at 0.5 h post-PCI,and were decreasing from 2.0 h post-PCI,then the serum levels of CXCL16 were declining to the levels of pre-PCI at 24.0 h post-PCI (P＜0.05).And the serum levels of NT-proBNP were rising from 0.5 h post-PCI,and the peak point was at 24.0 h post-PCI (P＜0.05).The postive relationships of the serum levels of CXCL16 and NT-proBNP to the serum levels of cTnT were confirmed by Pearson linear correlation analysis(P＜0.01).Conclusion Monitoring of soL-CXCL16 and NT-proBNP for patients with percutaneous coronary stenting could provide foundation for prognosis evaluation of PCI.
ABSTRACT
Epilepsy is a common neurological disease accompanied with laden economic burdens and heavy social resources consuming. Temporal lobe epilepsy (TLE) is an important subtype of the epilepsies. Our experiment was aimed to characterize the regional brain function alteration among the treatment na? ve TLE patients using ReHo. We found that elevated regional ReHo was in the left insula in the TLE patients, and the right one was cingulated, while the decreasing ReHo was in right putamen. Our result demonstrated that the key components associated with the epilepsy symptoms had altered the regional function in the TLE patients, and the disruption of cortex-thalamus-striatum loop. Our experiment provides evidence on the pathophysiological alteration in treatment na? ve TLE patients.