Curative effect of autologous periosteal iliac bone graft and allogeneic bone powder combined with PRP on HeppleⅤ talus osteochondral injury / 中国现代医生

@#Objective To analyze and compare the treatment of HeppleⅤ talus osteochondral injury(OLT)with autologous periosteal iliac bone graft and allogeneic bone powder combined with platelet rich gel(PRP).Methods Totally 62 HeppleⅤOLT patients admitted to our hospital from October 2018 to October 2022 were selected as the research subjects.They were divided into a transplantation group(31 patients received autologous periosteal iliac bone transplantation treatment)and a combination group(31 patients received allogeneic bone powder combined with PRP treatment)based on their treatment methods.Conduct a 12 month postoperative outpatient follow-up study on patients,evaluate and compare the treatment effectiveness,ankle joint range of motion(ROM),American Society of Orthopedic Foot and Ankle Surgeons(AOFAS)ankle posterior foot score,pain score,satisfaction,and incidence of complications between the two groups of patients at 12 months after surgery.Results The total effective rate of the transplantation group(96.77%)was not significantly different from that of the combination group(93.55%,P>0.05).At 12 months after surgery,the ROM and AOFAS scores of both groups improved(P<0.05),and there was no statistically significant difference between the groups(P>0.05).At 1 month,3 months,6 months,and 12 months after surgery,the pain scores of both groups decreased compared to before surgery(P<0.05).The subjective overall satisfaction of patients in the transplantation group(77.42%)was lower than that in the combination group(96.77%,P<0.05).The total incidence of complications in the transplantation group(19.35%)was significantly higher than that in the combination group(3.23%,P<0.05).Conclusion Allogeneic bone powder combined with PRP can avoid additional surgical incisions,increase patient subjective satisfaction,and increase the incidence of postoperative complications.

Prenatal ultrasound diagnosis and prognosis of fetal goiter: analysis of five cases / 中华围产医学杂志

Objective:To summarize the prenatal ultrasound features and prognosis of fetal goiter.Methods:The prenatal ultrasound findings and clinical data of five cases of fetal goiter in the Affiliated Hospital of Qingdao University from August 2018 to October 2022 were retrospectively analyzed regarding the sonographic features, concomitant signs, and prognosis using descriptive statistical method.Results:The five cases were first diagnosed as fetal goiter at 25-35 weeks of gestation, with all of them showing hypoechoic or medium echoic masses in the fetal anterior neck area. One case exhibited a central blood flow signal, early appearance of the distal femoral ossification center, tachycardia, increased cardiothoracic ratio during pregnancy, and developed postnatal hyperthyroidism. Three cases showed peripheral blood flow signals and had postnatal hypothyroidism, one of which had delayed appearance of distal femoral ossification center and increased cardiothoracic ratio. One case showed a peripheral blood flow signal with normal thyroid function after birth. Among the five cases, tracheal compression and polyhydramnios were found in one case; neck hyperextension was found in three cases. After treatment, the size of goiters did not change or shrunk in three cases and increased with the gestations in one case. One case did not receive any prenatal treatment and was born through cesarean section due to late detection and increased cardiothoracic ratio. Two cases underwent cesarean section at 35 gestational weeks, one had full-term cesarean section, and two delivered vaginally at term. Hyperthyroidism in one neonate was caused by excessively elevated maternal thyrotropin receptor antibody. Three cases of hypothyroidism occurred due to maternal antithyroid medication whose thyroid function recovered after supplementation of thyroxine. The thyroid function was normal in the rest of the baby. During the follow-up from 9 months to 4 years and 11 months old, no abnormalities in the intellectual and motor development of the five children were found.Conclusions:Fetal goiter often exhibits hypochoic or medium echoic mass in the anterior neck during prenatal ultrasonography. The fetal thyroid function could be evaluated according to different blood flow patterns and the presence of the ossification center. The prognosis of fetal goiter is good after active prenatal treatment.

Prevalence and characteristics of overweight and obesity in Chinese children aged 0-5 years / 中华流行病学杂志

Objective: To study the prevalence and characteristics of overweight and obesity among Chinese children aged 0-5 years, in 2010-2013. Methods: Data was from the'China Nutrition and Health Surveillance-0-5-Years-Old Children and Lactating Women'project in 2013. Stratified multistage cluster sampling method was used to select 55 districts/counties from 30 provinces (autonomous regions, municipalities) with the sample size of children as 32 862. Definition of overweight and obesity were according to both the WHO 2006 growth standard in children less than 5-year-old and the WHO 2007 growth reference in children of 5-years-old. Results: were calculated by complex weight based on national census from the National Bureau of Statistics in 2010. Results The overall prevalence of overweight was 8.4% among the 0-5-year-old in 2013, with 9.4% in boys and 7.2% in girls. Both of the rates from urban and rural areas were the same, as 8.4%. The prevalence rates of overweight in the 0-, 6-, 12-, 24-, 36-, 48- and 60-71 months age groups appeared as 13.0%, 11.1%, 8.3%, 6.0%, 4.8%, 3.9% and 15.9%, respectively. The rates of overweight in low, medium and high income families were 8.0%, 8.8% and 8.9%, respectively. The prevalence of obesity was 3.1% among the 0-5-year-old, with 3.6% in boys and 2.5% in girls. There was no significant difference seen in urban (3.3%) and rural areas (2.9%). The prevalence rates for obesity in the 0-, 6-, 12-, 24-, 36-, 48- and 60-71 months age groups were 5.8%, 3.8%, 2.5%, 1.6%, 1.2%, 1.3% and 7.8%, respectively. The rates of obesity in low, medium and high income families were 2.8%, 3.3% and 3.5%, respectively. Conclusion: The prevalence rates of both overweight and obesity were increasing among the 0-5-year-olds in China, suggesting that it is necessary to timely conduct the surveillance and intervention programs on overweight and obesity in this target population.

Epidemiological characteristics of waist circumference and abdominal obesity among Chinese children and adolescents aged 6-17 years / 中华流行病学杂志

Objective: To analyze the epidemiological characteristics of waist circumference and abdominal obesity among Chinese children and adolescents aged 6-17 years. Methods: Data was from the samples of aged 6-17 years in the China National Nutrition and Health Surveillance program in 2010-2012. P(90) (the same age, the same sex) was used as the diagnostic value for abdominal obesity. Results: The overall waist circumference of children and adolescents in all the age groups appeared higher in males than that in females (P<0.000 1), higher in cities than that in the rural areas (P<0.05), and higher in children with high family income than those with middle or low family incomes (P=0.000 3). The rate of abdominal obesity in children and adolescents aged 6-17 years appeared as 11.2% on average and 10.7% and 11.8% for boys and girls, respectively but with no significant difference (P>0.05). Rates on abdominal obesity appeared as 13.2% and 8.5% for boys while as 12.3% and 11.2% for girls respectively, in urban or rural areas. As for the levels of family income, the abdominal obesity rates appeared as 15.8%, 11.5% and 8.8% respectively for boys while 13.5%, 11.9% and 11.6% respectively for girls, under high, middle and low levels of family income. Conclusion: The rate of abdominal obesity in boys seemed more responsive to the impact of income in urban or rural areas.

Study on the relationship between family-related factors and obesity of children and adolescents aged 6-17 years / 中华流行病学杂志

Objective: To analyze the relationship between family-related factors and the status of overweight and obesity in children and adolescents aged 6-17 years in China. Methods: Data were collected from the China National Nutrition and Health Surveillance in 2010-2012 program. A sample of 6 343 subjects aged 6-17 years was selected, with matched weight, education levels, household income and other family related factors of their parents. Univariate analysis and multivariate logistic regression were used to explore the relationship between family factors and overweight and obesity in school-aged children and adolescents. Results: After adjusted for age, gender and region, results from the multivariate logistic regression showed that both the overweight and obesity of children and adolescents were associated with maternal BMI (OR=1.83, 95%CI: 1.63-2.05), paternal BMI (OR=1.74, 95%CI: 1.57-1.94), mother's educational level (OR=1.24, 95%CI: 1.12-1.37) and household income (OR=1.30, 95%CI: 1.15-1.46). Conclusion: Factors as overweight or obesity status of the parents, mother's educational level and household income were positively correlated with the prevalence of overweight and obesity in Chinese children and adolescents.

Epidemiological characteristics of overweight and obesity in Chinese children and adolescents aged 6-17 years / 中华流行病学杂志

Objective: To analyze the prevalence rates of overweight and obesity in Chinese children and adolescents aged 6-17 years, and to provide scientific basis for the development of prevention strategies on obesity. Methods: Data was from children and adolescents aged 6-17 years in the China National Nutrition and Health Surveillance 2010-2012 program. In children aged 6 years, criteria of overweight and obesity were followed the WHO growth reference for school-aged children and adolescents. In children and adolescents aged 7-17 years, overweight and obesity were defined by sex and age specific BMI, recommended by Guidelines for prevention and control of overweight and obesity among school-age children and adolescents according to the Chinese guidelines. Results: The overall rates on overweight and obesity were 9.6% and 6.4% among the Chinese children and adolescents aged 6-17 years, with 11.0% (12.8% for boys and 9.0% for girls) in urban and 7.7% (boys 9.7%, girls 5.5%) in rural areas. The rates of overweight and obesity among children and adolescents were 8.4% (boys 9.3%, girls 7.4%) and 5.2% (boys 6.2%, girls 4.1%) in the rural areas. According to the levels of household income, the overweight rates of children in high, middle and low incomes were 12.3%, 10.7% and 8.2%, with obesity as 8.6%, 7.2% and 5.7% respectively. Conclusions: In 2012, the prevalence rates of overweight and obese were 9.6% and 6.4% among children and adolescents aged 6-17 years, respectively, higher in urban than in rural areas and higher boys than in girls. The prevalence rates of overweight and obesity seemed to be related to the levels of household income.

The drinking status and associated factors in adults in China / 中华流行病学杂志

Objective: To investigate the drinking status and associated factors in adults in China. Methods: Based on the 2010-2012 China National Nutrition and Health Survey (CNNHS), a total of 135 824 participants aged ≥18 were included in this cross-sectional analysis. Multivariable logistic regression model was used to investigate the associated factors for drinking status. Results: The overall drinking rate was 30.5% in Chinese adults, 53.8% in men, and 12.2% in women. The excessive drinking rate was 14.0% in men and 1.1% in women. The daily drinking rate was 25.7% in men and 10.9% in women. Men mainly consumed multi-type wines, but women preferred beer. The overall harmful drinking rate was 7.1%. The excessive drinking rate, daily drinking rate, and harmful drinking rate increased first but then declined with age. All the four rates were positively related with physical activity. Conclusions: The drinking rate, excessive drinking rate, daily drinking rate and harmful drinking rate were high in adults in China. Drinking status was associated with age, sex, marital status, education level, smoking status and physical activity.

Prevalence and characteristics of overweight and obesity in Chinese children aged 0-5 years / 中华流行病学杂志

Objective To study the prevalence and characteristics of overweight and obesity among Chinese children aged 0-5 years,in 2010-2013.Methods Data was from the ‘China Nutrition and Health Surveillance-0-5-Years-Old Children and Lactating Women’ project in 2013.Stratified multistage cluster sampling method was used to select 55 districts/counties from 30 provinces (autonomous regions,municipalities) with the sample size of children as 32 862.Definition of overweight and obesity were according to both the WHO 2006 growth standard in children less than 5-year-old and the WHO 2007 growth reference in children of 5-years-old.Results were calculated by complex weight based on national census from the National Bureau of Statistics in 2010.Results The overall prevalence of overweight was 8.4％ among the 0-5-year-old in 2013,with 9.4％ in boys and 7.2％ in girls.Both of the rates from urban and rural areas were the same,as 8.4％.The prevalence rates of overweight in the 0-,6-,12-,24-,36-,48-and 60-71 months age groups appeared as 13.0％,11.1％,8.3％,6.0％,4.8％,3.9％ and 15.9％,respectively.The rates of overweight in low,medium and high income families were 8.0％,8.8％ and 8.9％,respectively.The prevalence of obesity was 3.1％ among the 0-5-year-old,with 3.6％ in boys and 2.5％ in girls.There was no significant difference seen in urban (3.3％) and rural areas (2.9％).The prevalence rates for obesity in the 0-,6-,12-,24-,36-,48-and 60-71 months age groups were 5.8％,3.8％,2.5％,1.6％,1.2％,1.3％ and 7.8％,respectively.The rates of obesity in low,medium and high income families were 2.8％,3.3％ and 3.5％,respectively.Conclusion The prevalence rates of both overweight and obesity were increasing among the 0-5-year-olds in China,suggesting that it is necessary to timely conduct the surveillance and intervention programs on overweight and obesity in this target population.

Epidemiological characteristics of waist circumference and abdominal obesity among Chinese children and adolescents aged 6-17 years / 中华流行病学杂志

Objective To analyze the epidemiological characteristics of waist circumference and abdominal obesity among Chinese children and adolescents aged 6-17 years.Methods Data was from the samples of aged 6-17 years in the China National Nutrition and Health Surveillance program in 2010-2012.P90 (the same age,the same sex) was used as the diagnostic value for abdominal obesity.Results The overall waist circumference of children and adolescents in all the age groups appeared higher in males than that in females (P＜0.000 1),higher in cities than that in the rural areas (P＜ 0.05),and higher in children with high family income than those with middle or low family incomes (P=0.000 3).The rate of abdominal obesity in children and adolescents aged 6-17 years appeared as 11.2％ on average and 10.7％ and 11.8％ for boys and girls,respectively but with no significant difference (P＞0.05).Rates on abdominal obesity appeared as 13.2％ and 8.5％ for boys while as 12.3％ and 11.2％ for girls respectively,in urban or rural areas.As for the levels of family income,the abdominal obesity rates appeared as 15.8％,11.5％ and 8.8％ respectively for boys while 13.5％,11.9％ and 11.6％ respectively for girls,under high,middle and low levels of family income.Conclusion The rate of abdominal obesity in boys seemed more responsive to the impact of income in urban or rural areas.

Study on the relationship between family-related factors and obesity of children and adolescents aged 6-17 years / 中华流行病学杂志

Objective To analyze the relationship between family-related factors and the status of overweight and obesity in children and adolescents aged 6-17 years in China.Methods Data were collected from the China National Nutrition and Health Surveillance in 2010-2012 program.A sample of 6 343 subjects aged 6-17 years was selected,with matched weight,education levels,household income and other family related factors of their parents.Univariate analysis and multivariate logistic regression were used to explore the relationship between family factors and overweight and obesity in school-aged children and adolescents.Results After adjusted for age,gender and region,results from the multivariate logistic regression showed that both the overweight and obesity of children and adolescents were associated with maternal BMI (OR=1.83,95％ CI:1.63-2.05),paternal BMI (OR=1.74,95％CI:1.57-1.94),mother's educational level (OR=1.24,95％CI:1.12-1.37) and household income (OR=l.30,95％CI:1.15-1.46).Conclusion Factors as overweight or obesity status of the parents,mother's educational level and household income were positively correlated with the prevalence of overweight and obesity in Chinese children and adolescents.