ABSTRACT
Ongoing and rapid development in medical science makes the improvement of English language abilities crucial for students. The paper sets out now to:develop excellent teaching methods, form a qualified and dedicated teaching faculty, focus on individual teaching methods, make English interesting and popular among students, and manage the process to maximize the value of the investment.
ABSTRACT
Retinoid acid and its derivatives have shown promising perspective in clinical use and lab research on the leukemia and other solid tumor cells.Some of these compounds have a stronger apoptotic potential,a lower level of cytotoxicity and a better pharmacokinetic profile than all-trans retinoic acid.The apoptosis pathways induced by these compounds are different from traditional p53-dependent pathway which recruited by many chemotherapeutics.Due to its specific molecular mechanism,these compounds could induce apoptosis in retinoic acid-resistant or multi-drug-resistant tumor cells.This paper reviews the current research on apoptosis induced by analogues of retinoid acid.