ABSTRACT
Objective To explore the clinical characteristics,management and pregnancy outcome in patients with ovarian tumor and ovarian tumor like condition complicated with pregnancy.Methods The clinical data of 248 patients with ovarian tumor and ovarian tumor like condition eomplicated with pregnancy who treated,operated and pathology conducted from January 2003 to December 2009 was analyzed retrospectively.Results Among of 248 patients,8 patients were found by pelrioscopy,184 patients were found by sonography.The rate of ovarian tumor and ovarian tumor like condition during pregnancy was 0.49％ (248/50 652),about 52.82％(131/248)were diagnosed as benign tumor,most of them were ovarian mature teratoma(22.18％,55/248).About 45.56％(113/248)were diagnosed as ovarian tumor like condition,most of them were ovarian chocolatecyst(23.79％,59/248).Four patients(1.61％,4/248)were ovarian malignant tumor.Two hundred and sixteen received operation,term birth was in 164 patients,premature birth was in 19 patients,miscarriage was in 33 patients.Conclusions Pelvioscopy and sonogaraphy are principally important in the diagnosis and detection of ovarian tumor during pregnancy.Pregnancy complicated with ovarian tumor or ovarian tumor like condition should be treated by tumor resection.Suitable surgery intervention during second trimester is safe.
ABSTRACT
Objective To study the expression and clinical significance of transforming growth factor-beta1(TGF?1) and its receptors(TGF?RⅠ and TGF?RⅡ) in placentas of pregnancy-induced hypertension(PIH). Methods Immunohistochemistry (SABC) was used to determine the distribution and intensity of TGF?1,TGF?RⅠ,TGF?RⅡ staining in placentas of 64 cases of PIH patients (21, 20 and 23 of mild, moderate and severe cases, respectively) and 20 cases of normal gravidas. Results The expression of TGF?1,TGF?RⅠ and TGF?RⅡ in placental trophoblasts and decidual cells was significantly increased in PIH group compared with the normal group (TGF?1:70.31% vs 35.00%,P