ABSTRACT
Background: Histologically, various subtypes of basal cell carcinoma (BCC) have been described which include superficial, nodular, keratotic, basosquamous, adenoid, cystic, and morpheiform. Objectives: The objectives of this study were as follows: (1) To find out the histological types of BCC prevalent in our population and (2) to study the clinical profile of these patients regarding age, sex, location, and clinical diagnosis. Materials and Methods: A 3-year retrospective study was carried out in the histopathology section of a tertiary care teaching hospital. The clinical data pertaining to the cases were compiled and studied. H and E stained slides were reviewed and some were recategorized according to the WHO classification. The results were analyzed using descriptive statistics. Results: Of a total of 67 skin tumors, 34 were malignant. Of these, BCC comprised 44.1% (15 cases). The most common location of BCC was the face (53.3% of the cases). The average age of the patients was 54.5 years. Histological types included nodular, adenoid, infiltrative, nodulocystic, basosquamous, keratotic, superficial, and BCC with adnexal differentiation. Nodular BCC was the most commonly encountered type in our setting, followed by adenoid BCC. Clinical diagnosis correlated with histopathologic findings in 33.3% of cases. Conclusion: This study highlights the morphological spectrum of BCC in our population and emphasizes the role of histopathological examination to prevent misdiagnosis of these tumors.
ABSTRACT
Introduction: Sebaceous carcinoma is a very rare malignant tumor primarily found in the area of the eyelid. We have reported here a case of sebaceous carcinoma of the eyelid with neck node metastasis diagnosed on fine needle aspiration cytology with emphasis on the unique cytomorphology of this tumor.Case history: A 35 year old woman presented with complaints of swelling in left upper eyelid, proptosis, loss of vision and cervical node enlargement. Fine needle aspiration (FNA) from the mass showed scattered and loose clusters of pleomorphic cells with increased nucleocytoplasmic ratio, prominent nucleoli, and abundant dense as well as vacuolated cytoplasm in a lipid backgound. A diagnosis of sebaceous carcinoma with cervical metastasis was made and confirmed on histopathology.Conclusion: FNA is a simple, cost effective technique for diagnosis of eyelid tumors. Familiarity with the cytomorphological features of sebaceous carcinoma can lead to early diagnosis of this malignancy with minimum discomfort to the patient