Numbers of plaque forming cells-IgG in peripheral blood of patients with chronic hepatitis B virus [HBV] infection

Numbers of PFC-IgG were enumerated in the peripheral blood of different groups of patients having chronic infection with HBV. In this study we included eight patients of chronic hepatitis B [CHB], seven HBV-healthy carriers, seven patients with autoimmune chronic active hepatitis [AICAH] that had many markers of HBV in their sera and ten healthy humans [control group] were investigated. A significantly [P<0.001] increased number of PFC-IgG in the peripheral blood of AICAH was observed as compared to the control group. No such difference was observed in the other two groups of patients [CHB and HBV-HC].