ABSTRACT
Introduction Along with the changes occurred in nutrition, climate over the years, the prevalence of blood disorder related diseases, such as Аllergic purpura (AP), Idiopathic thrombocytopenic purpura (ITP) is increasing. The current perspective of health service is focused on the treatment of AP and ITP by using combined therapeutic methods of modern and Mongolian medical approach. Mongolian traditional medicine has an advantage of reducing complications in reducing the recovery duration and also preventing from re-occurrence. Consequently, there is a need for investigation of formulating clinically effective preparation that complies with pharmaceutical standards. Objective The objective of this study was to develop the technology to obtain Tsusan Bolor capsules and establish its some quality criteria indicators. Materials and Methods The medicinal raw materials Gardenia Jasminoides Ellis, Rubia cordiofolia L, Picrorhiza serophulariflora Pennell, Arnebia guttatа, Crocus sativus, L, Pulvis Cornus Bubali and Artificial Bezoar were provided by Traditional medicine factory of the Inner Mongolian University for Nationalities, PRC. The L9(34) experiment test was used to obtain the extracts from crude medicinal plants and TLC, HPLS and pharmacopeias methods were used for the establishing quality criteria indicators of the capsules. Results Within the technological study the appropriate methods to obtain alcohol and water extracts from the medicinal raw materials and the technological scheme to obtain Tsusan bolor capsules were developed. As the results of quality criteria investigation indicated, the total content of gardenia glycoside is 1.71±0.02 mg, water content- 6.25±0.1%, heavy metal and arsenic content less than 10 μg/g and 2μg/g and disintegration time of the capsules is 20±3.
ABSTRACT
INTRODUCTION: One of the main issues on the National drug policies in countries of the world and in Mongolia is the proper usage of the drug. In this frame, we need to study and to implement the methodical basis to use drug market drug marketing theoretical principles . They are: to improve and to follow new standard in diagnostics and diseases treatments prevailing in our country, to stop inappropriate usage of drugs, to implement the drug program of national necessity, to determine the drug usage in the proper way, and to organize the control properly. According to the statistic report of 2002 through 2008, the rate of skin disease was ranked as 8 (4.5%) among common diseases, and as 7th (4.07%) among aimag level, but on the other hand the skin disease rate has increased by 59213 cases compared between 2002 and 2008. GOAL AND OBJECTIVES: The main goal of the study was to determine the drug needs used in dermatological diseases where the results were compared with the current standard and to develop future recommendations to improve the proper usage of medicines. MATERIALS AND METHODS: In order to calculate the drug cost and demands, the main marketing methods were used such as calculation of past, current and future prognosis of drug demands. For example: ∎ The calculation of drug expenditure ∎ Calculation of drug demands by number of registered disease cases ∎ Development of the future prognosis of the disease based on the assessment of experts RESULTS: 1092 patients who were hospitalized in 2007 and 2008 in National Center of Dermatology, 464 patients who were hospitalized in the epidermis department of the general hospital of 12 provinces, totally 1725 patient’s medical histories were chosen for drug usage in this research work. Average, patient day 12,7, males 867(50,3%) females 858(49,7%) children 283 (16,4%), adults 1442 (83,6%) participated in the research work. From all patients who are hospitalized are: patients who are in the hospital for the first time 1090 (63,2%), patients hospitalized for the second time 635 (36,8%). About patients who discharged from the hospital: 1055(61,2%) patients were recovered, and 670 (38,8%) patient’s health conditions were improved. Here is the approved diagnosis in the frame of the research work: dermatitis 605 (35.1%), Psoriasis 355 (20,5%), eczema 266 (15.4%) is leading the list. DISCUSSION: According to research on the drug proper usage, each drug used for patients treatment was calculated upon the drug type, quantity, and patients percentage and it is concluded by its classification of analogical quantification. They are: Patient percentage who treated and recovered with preparations against Gistamin 62.8, Patient percentage who treated and recovered with antibiotics and preparations against bacterium 72.8, Patient percentage who treated and recovered with drugs of Corticosteroid group 87.4, Patient percentage who treated and recovered with viricide 16.9, Patient percentage who treated and recovered with antidote and sorbent 21, Patient percentage who treated and recovered with drugs promoting the body organs, organ system functions 81.7, Patient percentage who treated and recovered with Preparation for skin casting 51, Patient percentage who treated and recovered with disinfection preparations 45.