ABSTRACT
Study was conducted in experimental mice to investigate acute and subchronic toxicity of “thach vi gia giam” remedy with liquid ointment form on their blood formation system and liver-kidney functions. The results showed that: LD50 toxic dose by oral route with maximum dose of 125 ml/kg mice weight could not been determined. With dose of “Thach vi gia giam” 50 ml/2kg (25 times higher than human dosage) during 2 months continuously, there was not a significant sigh of the changes in blood component, liver-kidney function compared with control group in a same condition.
Subject(s)
Ointments , Ointments/toxicityABSTRACT
The study was made on 42 benign prostatic hyperplasia patients. The results showed that after one month therapy by traditional medication, symptoms scoring index IPSS reduced from 21.0 to 11.71 (p<0.05). The flow of urinary increased from 4.56ml/s to 8.98ml/s (p<0.05). Residual urine volume reduced from 16.52ml to 8.35ml (p<0.05). The therapeutic outcomes by the extract of "Than khi hoan gia giam" were classified as follows: Good in 23 cases (54.8%), Moderate in 15 cases (35.7%), Poor in 4 cases (9.5%).