ABSTRACT
To establish an association between the angle of mandible on an orthopantomogram [OPG] with reduced bone mineral density of femoral neck and spine on Dual Energy X-ray Absorptiometry [DXA] scan. Cross-sectional study. Institute of Basic Medical Sciences [IBMS], Dow University of Health Sciences [DUHS], Karachi, from December 2011 to July 2012. Female subjects between 25 and 85 years of age were divided into premenopausal [Group-I] and postmenopausal [Group II] groups. Dual Energy X-ray Absorptiometry [DXA] scan was done to divide Group-I and Group-II into normal [pre A, post A], osteopenic [pre B, post B] and osteoporotic [pre C, post C] groups. Changes seen in angle of mandible on orthopantomogram [OPG] in subgroups of Group-I were compared with each other and with subgroups of Group-II. SPSS version 16 was used to carry out the statistical analysis. Intragroup significance was evaluated through One Way Analysis Of Variance [ANOVA]. For intergroup significance independent samples t-test was applied. The angle of mandible [A] was significantly decreased in Intragroup comparison of Group-II [0.035] between Post normal [Post A] vs. Post osteopenic [Post B] groups. Intergroup comparison between Group-I and Group-II [0.005] showed a significant decrease in angle of mandible between Pre osteopenic [Pre B] vs. Post osteopenic [Post B]. As decrease in angle of mandible was observed at stage of osteopenia, it can be conveniently used for early detection of osteoporosis
ABSTRACT
To see whether the cortex of mandible on an OPG can be employed for early detection and screening tool for osteoporosis. Cross sectional study. The study was conducted in IBMS, DUHS Karachi and stretched over a period of eight months from December 2011 to July 2012. One hundred and seventy four female subjects, aged 25 to 85 years, were divided into premenopausal [Group I] and postmenopausal [Group II] groups. Each group was subdivided into normal [pre A, post A], osteopenic [pre B, post B] and osteoporotic [pre C, post C] groups by Dual Energy X- ray Absorptiometry [DXA] Scan. Mandibular morphological changes seen on OPG in subgroups of Group I were compared with each other and with subgroups of Group II. Cortical thickness at mental foramen [CMF] was observed on OPG. Statistical analysis was performed by SPSS version 16 using One Way Analysis Of Variance [ANOVA] to evaluate intra group significance and for intergroup significance independent samples T-test was applied. The thickness of Mandibular cortex at mental foramen [CMF] was found to be significantly decreased in osteoporotic patients. In conclusion a simple method of screening was established which can be used as early detector of osteoporosis in a cost effective manner