1.
Indian J Biochem Biophys
;
1989 Dec; 26(6): 405-9
Article
in English
| IMSEAR
| ID: sea-26757
ABSTRACT
QSAR studies using molecular connectivity and van der Waal volume have been performed on a new series of hydroxyguanidine derivatives and a series of isoindolediones. Regression analysis has shown that anticancer and antiviral activity of hydroxyguanidines as well as cytostatic activity of isoindolediones correlate well with both the structural parameters.
Subject(s)
Antineoplastic Agents , Antiviral Agents , Chemistry, Physical , Chemical Phenomena , Structure-Activity Relationship
2.
Indian J Biochem Biophys
;
1989 Jun; 26(3): 199-200
Article
in English
| IMSEAR
| ID: sea-29017
ABSTRACT
QSAR studies have been performed on the homologues of 3-triazines, using molecular connectivity index and van der Waal volume as structural parameters. The regression analysis has shown good correlation between antitumour activity and the two structural parameters.