[ effect of Dorema aucheri extract on breast tumor induced by DBMA in rats]

Dorema aucheri is from the piaceae family that exists in margins of Zagros mountains in Iran. In this study, the effect of 200 and 400 mg doses of Dorema aucheri extract on DMBA induced breast tumors in rats was investigated. This experimental study, was conducted in Herbal Medicine Research Center of Yasuj University of Medical Sciences. Forty rats were allocated in experimental and control groups. In experimental groups, after receiving DMBA, Dorema aucheri alcoholic extract in doses of 200 and 400 mg/kg of body weight were used orally for 12 weeks. One group of control animals received DMBA only and the other group received 200 mg of Dorema aucheri extract. At the end of 12 weeks, the tumor mass was isolated and evaluated by hematoxylin eosin histology staining. The average tumor size, number of tumors, and histology of tumors in groups were compared. The gathered data were analyzed using SPSS version 18, using ANOVA and Paired T test. Mean of tumor number were significantly different in experimental and control groups. No tumor was seen in control group which received 200 mg of the extract while breast tumor was seen in other groups. Mean of tumor number in animals which received 400 mg of extract was significantly higher that the other groups [p<0.05]. It seems that the dose of 400 mg extract of Dorema aucheri increases the tumor size, causes weight loss, decreases longevity and durability of rats while dose of 200 mg of extract reduces the tumor growth and tumor necrosis in Sprague Dawley female rat's with breast tumor induced by DMBA

[Seroepidemiological study of brucellosis in high risk groups in Boyerahmad 1384]

Brucellosis is a zoonotic disease that may have a major public health and economic impact in most countries. The disease appears as a Malt fever in humans and abortion in animals. This study was designed to determine the serologic titer of Brucella in high risk and non high risk people in Boyerahmad. A retrospective seroepidemiological study was performed on samples collected from 604 high risk and non high risk people using Rose Bengol test, tube standard test as a rapid test and 2 mercaptoethanol [2ME] and comb's wright as a confirmatory test. The data collected were analyzed by X[2] test via SPSS. Seroprevalence of Brucellosis in high risk people appeared to be high in the Rose Bengal and tube standard test [TST] 6.62 at titer >/= 1/40 whereas for non high risk it was 0%. Confirmation test in high risk people was shown with 2ME in four people. Brucellosis is a major cause of disease in high risk people which can be due to direct or indirect contact with diary products of the related animals

[Rate of vaccination coverage in infants up to 12 months of age in kohgilouyeh and boyrahmad province 2000-2001]

Vaccination of children has been accepted as an appropriate and effective method of prevention the some serious diseases and a large number of countries all over the world have managed to perform it within their national framework of the health programs .Howevere due to the scope of health system of different countires, the coverage appeared to be of different magnitudes. The present study aimed at surveying the degree of vaccination coverage of children under one year of age in Kohgilouyeh and Boyrahmad province. In this crosss - sectional descriptive study a total number of 420 infants were selected through a random cluster sampling In 2000-2001. information about the subjects vaccination history was worked out using their vaccination cards. The data were analyzed employing descriptive statistict, Pearson Test and ANOVA. The study revealed a vaccination coverage of 90% to 99%. the coverage was 94.2% for the third term of oral drop of polio 94.2%, for the second term of DPT, 95.7% for the third term of DPT, 92.7% for the third term of hepatitis, 90.7% for measles, and 99.8% for BCG. The most important causes of delay in receiving the vaccines were reported to be lack of vaccine, season of migration, infants disease, remoteness and lack of transportation, raining, season of labor, and mother's disease. Vaccination coverage within the national programs and WHO protocols appears to be greatly useful and appropriate. However, to achieve this importance, appropriate planning and teaching both people and the health staff about the promotion and quality of the point is felt necessary

Vaccination coverage of children under 1 Year of age in the tribal community of Kohgiloyeh and BoyrAhmad Province [1382]

Vaccination of children under 1 year of age is one of the most important programs of the country at all levels of the health and treatment organizations. Due to geographical dispersion and movement during different seasons of the year, tribal societies are the most vulnerable communities in the field of health services and vaccination. This study aimed at determining the vaccination coverage of children under one year of age in the tribal society of Kohgiloyeh and Boyr Ahmad Province. This descriptive cross-sectional study was performed on all the newborns from the tribal society of kohkiloyeh and BoyrAhmad province who were under the age of one, born between 1.1.81 and 29.12.81. For data collection, a questionnaire was used which contained individual characteristics, types of routine vaccines, the data regarding the injections, and the possible reasons for delay in receiving vaccines.The questionnaire was tested for its content-validity. The total coverage of B.C.G vaccine was 97.1%. The total coverage of polio vaccine was 98.4%, 98.2% and 97.7% for the first, second and third doses, respectively, and it was the same for DPT vaccine. The coverage of hepatitis for the first, second, and third doses was 98.6%, 95.2% and 95%, respectively. The total coverage of polio vaccine at birth was 85.5%. AU the vaccines were received with delay. The highest delay was related to first dose [27.6 days] and second dose of hepatitis B [74.3 days], first dose of measles [295.4days] and the least delay was found in polio [10.9 days] and third dose of hepatitis [272.4 days]. The main reasons for delay were distance from vaccination station [27.3%], unavailability of health staff [262%] and the mother's lack of knowledge [14.2%]. Revision of the programs related to the monitoring of mobile teams of vaccination is necessary to improve the vaccination coverage in tribal communities. Moreover, more health staff is required in order to improve the present status of vaccination in tribal societies