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1.
Tunisie Medicale [La]. 2009; 87 (3): 196-199
in French | IMEMR | ID: emr-103570

ABSTRACT

While toxoplasmosis infection in women is often benign, transmission of maternal infection to the fetus can lead to severe sequelae. Because the majority of patients with acute toxoplasmosis are asymptomayic, a systematic serologic screening program will needed with monthly serologic screening of all seronegative pregnant women until delivery. The aim of this study was to identify cases of congenital toxoplasmosis among all live births of women found to be seronegative in pregnancy once at least. During a prospective study period of 16 months [from 07/02/2003 to 30/06/2004] we conduct a neonatal screening of all live births of women found to be seronegative in pregnancy once at least. Peripheral samples were obtained from every couple mother/ infant. Serological methods performed for diagnosis of toxoplasma specific IgM and IgG antibodies were Hemaglutination and Enzyme-linked immunosorbent assay [ELISA]. Four cases of congenital toxoplasmosis were diagnosed after birth. All cases were asymptomatic and a specific treatment was started soon after diagnosis. The clinical and serologic evolution was normal in three cases. A serologic rebound at two years was reported in one case with a chorioretinitis in the examination of the ocular fundus. Neonatal as well maternal screening during pregnancy and at birth should be systematic to prevent, diagnose and treat early the affected neonates usually asymptomatic


Subject(s)
Humans , Male , Female , Neonatal Screening , Prospective Studies , Immunoglobulin M , Immunoglobulin G , Enzyme-Linked Immunosorbent Assay , Serologic Tests
2.
Revue Maghrebine de Pediatrie [La]. 2008; 18 (2): 105-106
in French | IMEMR | ID: emr-108764

ABSTRACT

Upper gastrointestinal tract bleeding in the neonate is usually related to gastritis and esophagitis. Fewer cases of prenatal gastrointestinal tract bleeding diagnosis are reported, showing that gastric peptic lesions can occur in the prenatal period. We report a case of a prenatal oesophagitis revealed at 35 weeks of gestation by the presence of bloody amniotic fluid that was confirmed by endoscopy at birth


Subject(s)
Humans , Male , Prenatal Diagnosis , Infant, Newborn , Esophagitis/complications , Gastrointestinal Hemorrhage/diagnosis
3.
Maghreb Medical. 2007; 27 (383): 338
in French | IMEMR | ID: emr-134613

ABSTRACT

Aplasia cutis congenita is a congenital condition in which skin, bone, and dura can be absent with an estimate incidence of 1 in 10,000 births. The lesions may occur on any body surface although localised agenesis of the scalp is the most frequent pattern It occurs as an isolated defect or with other associated anomalies. We report 2 cases of ACC, one isolated and another with associated malformations


Subject(s)
Humans , Female , Infant, Newborn , Scalp/abnormalities
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