Influence of dietary lupin seed mixed diet on serum cholesterol level in normal and diabetic rabbits

Fractions of lupine seed were added to the diet of both normal and diabetic hypercholesterolemic rabbits for 8 weeks. The effects on blood glucose, plasma glucagon and plasma cholesterol levels were investigated. The lipid extract had no effect. The defatted fraction, which is rich in fibers [11.0%] and contains 0.3% of alkaloid, significantly lowered basal blood glucose, plasma glucagon and plasma cholesterol levels in normal rabbits. The addition of this fraction to the food of diabetic hypercholesterolemic rabbits caused a decrease of cholesterolemic and reduced hyperglycemia. In conclusion, the defatted portion of lupine seed induced a hypocholesterolemic effect

comparison of the effects of dietary fiber concentrated from carrot sunflower seed and wheat bran on the serum cholesterol and blood glucose response in cholesterol-fed rats

Wheat bran 80% ethanol-insoluble residues from sunflower seeds or carrot were incorporated in purified diets to reach a 6% fiber level. Cholesterol-fed rats were fed on either one of the fiber diets or a fiber-fee diet. Serum and HDL [high density lipoprotein]-cholesterol levels were unchanged. Blood glucose levels tended to be reduced. The 6% level of the tested fibers was well tolerated, but the weights of the heart, spleen and liver were significantly decreased by carrot, carrot and sunflower seed fiber and sunflower seed fiber, respectively, suggesting that the safety of these fiber concentrates needs further investigation