ABSTRACT
Monitoring glycemic status, as performed by patients and healthy care providers, is considered the cornerstone of diabetes care. Recent studies have shown that fasting plasma glucose [FPG] measurements alone do not provide an overall picture of disease prognosis and associated complications. This study was designed to evaluate the possibility of utilizing post-prandial glucose excursion test as a predictor of glycemic control during treatment with oral hypoglycemic agents in type 2 diabetes mellitus. This study was carried on 24 patients with type 2 diabetes mellitus ranked into good glycemic control group [12 patients] and poor glycemic control group [12 patients] according to the criteria of evaluation of FPG. Twelve healthy subjects were selected and served as controls for comparison of the studied parameters. Fasting levels of plasma glucose, C-peptide, glycated hemoglobin and post-prandial glucose excursion profile were measured. The results indicated that fasting plasma glucose [FPG] can not be used as only predictor for determining proper acute and chronic glycemic control during drug therapy of type 2 D.M. and post-prandial glucose excursion [PPGE] test was recommended as a more suitable procedure for diagnosis and treatment follow up of type 2 D.M. patients. PPGE test can be considered as a more convenient way to follow glycemic control status during treatment of type 2 DM