Relationship between changes of body mass index and the pattern of osteoanthritis

Relationship between changes of body mass index and the pattern of osteoarthritis. Short title of the study: changes of Body mass index and osteoarthritis patterns. To assess the relationship between overweight, obesity and different patterns of osteoarthritis of the Knee joints and generalized Osteoarthritis. The current study included two hundred and nine patients attending the medical and rheumatology clinics in Amiri hospital for the period from March 2009 to February 2010. The group consisted of 115 males and 94 females, after their consent was taken they were interviewed, examined for their height and weight] to measure body mass index [and radiographed for the presence of knee and generalized Osteoarthritis. The association between Osteoarthritis and weight was then assessed through calculating the body mass index and the results were analyzed. We found a strong association between increased body weight and knee Osteoarthritis in females [OR 3.28 [95% confidence interval [Cl], 2.07-5.36] 1 and a significant association with generalized OA in males [OR 1.88 [95% Cl, 1.24-2.92]] .Regarding joint symptoms [Arthralgia, Swelling or Stiffness] were found to be associated with obesity [P=0.0001]. It is concluded that Increased body weight is strongly associated with knee Osteoarthritis in females and with joint symptoms in all Osteoarthritis patients, there is a strong association between obesity and generalized Osteoarthnitis among males. Regarding the generalized Osteoarthritis we could not find correlation with obesity

Study of the relationship between obesity, body mass index and migraine: is it a possible risk factor

To assess the influence of body mass index [BMI] on the prevalence, attack frequency and clinical features of migraine. As well as studying the relationship between BMI and level of migraine-related disability. This is a cross-sectional comparative study of 437 patients reviewing the obesity clinic in primary care center and medical outpatient clinic in general hospital. The participants were divided into 4 categories based on BMI: normal weight [18.5-24.9], overweight [25.0-29.9], obese [30.0-34.9], and morbidly obese [>35.0]. Migraine prevalence and clinical features were assessed as a function of BMI. Among individuals with migraine, very frequent migraine attacks [10-14 d/mo] occurred in 16% of the overweight [OR 1.3], 44% of the obese [OR 2.9] AND 24% [OR 5.7] subjects, compared with 2% of those with normal weight. Among migrainures, 31.1% of those with normal weight had some disability compared with 36.9% of the overweight, 37.8% of the obese and 41.1% of the morbidly obese subjects. Our study support that obesity is an exacerbating factor for migraine and was propose that migraine and obesity may share same path physiological biological mechanisms that would be advices to undergo further researches to explore more about it

Serum phosphorus and magnesium levels in patients with metabolic syndrome

Metabolic syndrome is defined as the co-occurrence of at least three of the following features: hyperglycemia, hypertension, central obesity and dyshpidemia. It is considered an atherogenic cardiovascular risk factor that has recently become a public health problem. Disturbances in phosphate and for magnesium metabolism may have potential pathophysiological implication in the pathogenesis of this duster of cardiovascular risk factors. We performed a cross-sectional study to examine the relationship between serum phosphorus and magnesium levels in Kuwaiti patients with metabolic syndrome. Two hundred Kuwaiti individuals were entailed [109 subjects diagnosed as having metabolic syndrome and 91 as control group]. Their mean age was 48.6 +/- 9.9 years. Both males and females, smokers and non-smokers were included in our study. The diagnosis of metabolic syndrome was based on Adult treatment Panel III guidelines which includes central obesity, hyperglycemia, hypertension and dyslipidemia. Patients with metabolic syndrome showed significantly lower phosphate and magnesium levels compared with controls in addition to non significant differences in the rate of urinary excretion of phosphorus and magnesium between diabetics and control groups. We assume that hypophosphatemia and hypomagnesaemia patients with metabolic syndrome could be attributed to decreased directly intake, as well as internal redistribution of this clement. Kuwaiti Patients with. metabolic syndrome show significantly lower phosphate and magnesium levels compared with healthy individuals. These electrolyte disturbances could be considered as one of the diagnostic criteria for diagnosis of metabolic syndrome. In addition, this electrolyte imbalance may have a role in pre-vention and/or treatment of the metabolic syndrome. Further studies arc needed to support this finding