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Mansoura Medical Journal. 2005; 36 (1-2): 395-412
in English | IMEMR | ID: emr-200950

ABSTRACT

Background: Dyslipidemia is a modifiable risk factor for development and progression of coronary atherosclerosis. The role of dyslipidemia on the evolution of left ventricular dysfunction [LVD], heart failure [HF] and left ventricular thrombosis [LVT] following acute myocardial infarction [AMI] has not been stressed upon


Objectives: The purpose of this comparative study was to evaluate the ventricular systolic, diastotic functions and LVT in the dyslipidemic versus the non-dyslipidemic groups


Subjects and Methods: One hundred patients with firs attack AMI. We evaluated: Clinical, biochemical, alectrocardiography and echocardiographic graphic studies were undertaken


Results: The ejection fraction [EF] and fractional shortening [FS] were significantly lower with higher scores of wall motion abnormalities and increased LVT among the dyslipidemic Group


Conclusion: In patients with first attack AMI, dyslipidemia has a significant detrimental effects on left ventricular [LV] systolic function with significant higher tendency for development of LVT. These deleterious effects are more evident in males, relatively young age groups [<60 ys] and those with anterior wall AMi

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