Lemierre syndrome: an unusual complication of tongue cancer

An eighty-year-old female was admitted to the intensive care unit for hemorrhagic shock due to bleeding tongue malignancy. Clinical assessment revealed infected neoplastic lesion. Blood cultures on admission revealed Streptococcus spp. The diagnosis of Lemierre syndrome was suspected. Therefore, an ultrasound Doppler was performed and revealed thrombosed right internal jugular vein. The patient had a favorable outcome and improved with appropriate antimicrobial treatment

Xenomonitoring of Different Filarial Nematodes Using Single and Multiplex PCR in Mosquitoes from Assiut Governorate, Egypt

Wuchereria bancrofti, Dirofilaria immitis, and Dirofilaria repens are filarial nematodes transmitted by mosquitoes belonging to Culex, Aedes, and Anopheles genera. Screening by vector dissection is a tiresome technique. We aimed to screen filarial parasites in their vectors by single and multiplex PCR and evaluate the usefulness of multiplex PCR as a rapid xenomonitoring and simultaneous differentiation tool, in area where 3 filarial parasites are coexisting. Female mosquitoes were collected from 7 localities in Assiut Governorate, were microscopically identified and divided into pools according to their species and collection site. Detection of W. bancrofti, D. immitis, and D. repens using single PCR was reached followed by multiplex PCR. Usefulness of multiplex PCR was evaluated by testing mosquito pools to know which genera and species are used by filarial parasites as a vector. An overall estimated rate of infection (ERI) in mosquitoes was 0.6%; the highest was Culex spp. (0.47%). W. bancrofti, D. immitis, and D. repens could be simultaneously and differentially detected in infected vectors by using multiplex PCR. Out of 100 mosquito pools, 8 were positive for W. bancrofti (ERI of 0.33%) and 3 pools each were positive for D. immitis and D. repens (ERI 0.12%). The technique showed 100% sensitivity and 98% specificity. El-Nikhila, El-Matiaa villages, and Sahel Seleem district in Assiut Governorate, Egypt are still endemic foci for filarial parasites. Multiplex PCR offers a reliable procedure for molecular xenomonitoring of filariasis within their respective vectors in endemic areas. Therefore, it is recommended for evaluation of mosquito infection after lymphatic filariasis eradication programs.

Xenomonitoring of Different Filarial Nematodes Using Single and Multiplex PCR in Mosquitoes from Assiut Governorate, Egypt

Wuchereria bancrofti, Dirofilaria immitis, and Dirofilaria repens are filarial nematodes transmitted by mosquitoes belonging to Culex, Aedes, and Anopheles genera. Screening by vector dissection is a tiresome technique. We aimed to screen filarial parasites in their vectors by single and multiplex PCR and evaluate the usefulness of multiplex PCR as a rapid xenomonitoring and simultaneous differentiation tool, in area where 3 filarial parasites are coexisting. Female mosquitoes were collected from 7 localities in Assiut Governorate, were microscopically identified and divided into pools according to their species and collection site. Detection of W. bancrofti, D. immitis, and D. repens using single PCR was reached followed by multiplex PCR. Usefulness of multiplex PCR was evaluated by testing mosquito pools to know which genera and species are used by filarial parasites as a vector. An overall estimated rate of infection (ERI) in mosquitoes was 0.6%; the highest was Culex spp. (0.47%). W. bancrofti, D. immitis, and D. repens could be simultaneously and differentially detected in infected vectors by using multiplex PCR. Out of 100 mosquito pools, 8 were positive for W. bancrofti (ERI of 0.33%) and 3 pools each were positive for D. immitis and D. repens (ERI 0.12%). The technique showed 100% sensitivity and 98% specificity. El-Nikhila, El-Matiaa villages, and Sahel Seleem district in Assiut Governorate, Egypt are still endemic foci for filarial parasites. Multiplex PCR offers a reliable procedure for molecular xenomonitoring of filariasis within their respective vectors in endemic areas. Therefore, it is recommended for evaluation of mosquito infection after lymphatic filariasis eradication programs.

Application of hazard analysis and critical control point [HACCP] on mango pulp and mango juice

HACCP plan was established for mango pulp production and mango juice processing lines. Results showed that the number of aerobic, anaerobic bacteria, Bacillus cereus decreased from 5.0 x 10[4] CFU/g and 7.0 x 10[3] CFU/g to -ve, -ve, -ve respectively after HACCP in the mango pulp. Mold and yeast, Coliform group, E. coli and Staph. aureus were not found in mango juice either before or after HACCP. Aerobic and anaerobic bacteria were found before HACCP in mango juice. Verification procedures of cleaning and disinfection plan, controlling of critical control points[CCPs] and HACCP system through the microbiological tests were conducted. The results revealed that the microbial load was significantly decreased to the acceptable levels at all processing steps

Acute elastic recoil of coronary stents immediately after their implantation

The objective of this study was to evaluate the acute elastic recoil of coronary stents immediately [10 minutes] after balloon deflation, because of the close relation of this elastic recoil and the late restenosis of coronary stents. Forty patients with isolated coronary lesion were studied immediately after stenting following successful coronary angioplasty. Coronary angiography before stenting showed mean reference diameter of 2.23 +/- 0.58 mm and mean minimal lesion diameter of 0.65 +/- 0.35 mm with mean percentage stenosis of 70.7 +/- 9%. On the other hand, mean diameter of stent during balloon inflation was 2.37 +/- 0.8 mm, while mean duration of inflation through the stent was 15.3 +/- 4 seconds and mean pressure used for stent deployment was 13.6 +/- 4 bars. The immediate post stent angiography showed satisfactory results in all patients with mean stent diameter, 10 minutes after deployment of 2.02 +/- 0.30 mm and mean percentage elastic [ER] of 11.6 +/- 2.36%. All angiographic measures were done with the help of computer-based cardiovascular angiography analysis system [Artrex Image Comm]. The mean ER was much less than that previously reported after pTCA in previous studies and also better than that reported for post stenting in stress trial [11.6% vs 17%]. On the other hand, different types of stents were used [XT stents 17, NIR stents 12 and Palmaz Schatz stents 11] and they did not show any difference in absolute ER among the three subgroups according to the selected stent [XT = 0.51 +/- 0.49 mm, NIR = 0.45 +/- 0.41 mm and PS = 0.56 +/- 0.53 mm]. Furthermore, in this study, pressure up to 18 bars was used for stent deployment [13.6 +/- 4 bars] and this technique optimized stent opposition to the vessel wall increased final stent diameter and reduced elastic recoil and hence late restenosis

Protect your children by poison proofing your home

Preventable accidents if they happen are crimes. Accidental poisoning in home ranks at a front place. This study was undertaken to show to what extent our homes are poison proof. A total of 5100 questionnaire sheets, in City. Only 3850 sheets were completed and included in the study. Response to the questionnaire by doctors was 23.3%, while it was 97.0% and 97.l3% for the medical students and public, respectively. The study showed that 42.05 of the public do not keep potentially harmful household products [caustic Potash, Kerosene, insecticides' etc] in their original containers with labels kept on Also, failure of safety storage of household products and medicines in a special locked cabinet was reported by more than a third of public samples and more than half of the medical students and public samples [37.3%, 52.2%, and 61.7% respectively]. The author recommends issuing an educational program in home safety for primary schools, expected parents and the public. Unused medicines and drug items should be gathered by volunteer team and redistributed to those who are in need

efficacy of syrup of IPECAC as an emetic used by Alexandria Poison Center

The safety and effectiveness associated with the use of syrup of Ipecac in patients with acute poisoning has been well established. A study was carried out on 1811 conscious patients admitted to Alexandria poison center with diagnosis of [acute poisoning]. All patients were given a standard initial dose of syrup of Ipecac of 30 ml for adults and 15 ml for children. The study showed that syrup of Ipecac was effective in inducing emesis within 30 min in the majority of patients [98.4%] with a mean of 11.71 +/- 3.97 minutes. No complications at all happened to patients after its administration. The use of Syrup of Ipecac in the emergency departments of all hospitals dealing with the treatment of acute poisoning is highly recommended