ABSTRACT
To improve the dyeability and antimicrobial activity of cotton, the cotton was treated. Firstly, Carboxymethylation was carried out in the cotton fibers to form alkali cellulose. Due to carboxymethylation, the alkali cellulose modifies the crystalline structure of cellulose and increases the accessibility of fibers to chemicals by swelling. Secondly, it padded in a solution content (5 % nano zinc oxide, 4% citric acid) or (6 % titanium isopropoxide, 4% citric acid) or in a solution of 5 % nano zinc oxide, 6 % titanium isopropoxide, 4% citric acid or in a solution of 7% nano zinic oxide, 7% titanium isopropoxide, 4% citric acid, at wet pick up of ca 100%, then dried at 85 °C for 5 min., and cured at 100 °C for 3 min, the latter, we use these fabric in dyeing with synthesized acid dye and commercial basic dye finally, we measure antimicrobial activity for these fabric toward Gram negative and Gram positive.
ABSTRACT
Herein we describe the preparation, characterization and utilization of chitosan nanoparticles for the intracellular delivery of the poorly cell-penetrating antibiotic e.g. Ciprofloxacin, Chlortetracycline hydrochloride and Gentamycin sulfate to improve their treatment of bacterial infections. Chitosan nanoparticles were prepared via the ionic gelation of chitosan with tri polyphosphate anions. Several parameters were studied to optimize the particle size of chitosan nanoparticles, here we select the concentration of chitosan and the concentrations of sodium tri poly phosphate (TPP) as optimizing parameters and the other factors stay constant such as pH of solution and ultrasonication time. Chitosan nanoparticles formed characterized by using FT-IR and transmission electron microscope (TEM). Results show that chitosan nanoparticles and its loaded antibiotics kill and inhibits the growth of gram (+) and gram (-) bacteria tested due to nanoparticles structures, and the antibacterial activity increased with increasing the anti biotic content.