ABSTRACT
The majority of oesophageal cancer cases occur in developing countries. Globally males predominate. This study aims to review the clinical aspects of oesophageal carcinoma in Sudanese patients referred to endoscopy in Gezira, Central Sudan. Data were collected from patients who underwent endoscopy during the period from 2005 to 2007 at The Gezira Centre for Gastroenterology Endoscopies and Laparoscopic Surgery. Demographic and clinical data including; sex, age, locality of residence, clinical presentation, tumour site and morphology were collected and analysed. Seven hundred and two patients were consecutively referred to our centre for endoscopy. Seventy-three out of 702 patients [9.6%] referred for endoscopy proved to have oesophageal cancer. Fifty-five out of 73 patients [75.3%] were females generating a male to female ratio of 1:3.3. The mean age of females was 52.75 +/- 11.66 years and that of males was 66.11 +/- 9.52. Sixteen [21.9%] patients came from the Managil; 14 [19.2%] from Hasaheesa and Rufaa; 14 [19.2%] from Blue Nile; 10 [13.7%] from Wadmedani [Central Sudan] and 19 [26%] from Elfaw and Kassala. In most cases [75.3%], the tumours were located in the middle third of the oesophagus. 79.5% of the tumours were squamous cell type. Patients referred for endoscopy to The Gezira Centre for Gastroenterology, Endoscopies and Laparoscopic Surgery in Gezira revealed a greater proportion of women than of men diagnosed with the disease [1:3.3]. More studies are needed to investigate the epidemiology of this disease and to identify the reason for the apparent gender uneven manifestationi
ABSTRACT
To study the histological patterns of nasopharyngeal carcinoma NPC in Sudanese patients and to compare them with the internationally published series. A retrospective review for records of NPC patients treated in the Institute of Nuclear Medicine, Molecular Biology and Oncology INMO, Wadmedani, Sudan, during the period 2000-2005 was conducted. Parameters included in the review were histological types of NPC according to the World Health Organization WHO classification, age, gender, locality, ethnicity, and stage. All cases of NPC with positive histology were included while other types of histology lymphoma, sarcoma were excluded. The SPSS software was used for data entry and analysis. Total number of patients with NPC was 103. Age range from 11-82 years, median was 41 years, and mean was 45.5 years of age. Male:female ratio was 2:1. The WHO histology type-3 was 73.8% of cases, WHO type-2 was 26.2%, and there was no case of WHO type-1 found in this study population. Neck swelling is the most common presenting symptom 77.8%.Pattern of NPC classification resembles those seen in endemic areas like South China. Dominant histology was WHO type-3. Identifying risk factors for NPC in Sudan is required