ABSTRACT
Background: Infertility is one of the major social issues. Due to the asymptomatic cervical infection associated with Staphylococcus aureus [S. aureus], the majority of patients remain undiagnosed. The present study intended to assess the frequency of S. aureus isolated from infertile women's endocervix in northwest Iran
Materials and Methods: In a descriptive cross sectional study, specimens were randomly collected during vagina examination using a sterile speculum and swabbing. After performance of antibiotic susceptibility testing, polymerase chain reaction [PCR] was used to identify methicillin-resistance S. aureus [MRSA] and toxic shock syndrome toxin-1 [TSST-1]
Results: About 26 [26%] and 9 [9%] women's urogenital tracts were colonized by S. aureus and Candida spp., respectively, of which three [11.5%] patients were infected with fungi and S. aureus, simultaneously. Antibiotic susceptibility results showed high activity of vancomycin and co-trimoxazole on isolates. Regarding PCR results, mecA sequences were detected in 7 [26.9%] strains, whilst the tst gene encoding TSST-1 was not detected in any of clinical strains
Conclusion: The prevalence of S. aureus was very high in infertile women. Therefore, it demands all patients undergoing infertility treatment to be investigated thoroughly for this type of infection