Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add filters








Year range
1.
Article | IMSEAR | ID: sea-210339

ABSTRACT

Background:Diabetes population in Sudan is around one million 90% have type 2 diabetes. In Sudan diabetes is as increasing problem, being responsible for 10% of hospital admission and mortality.Measurement of zinc and copper is an important in decrease development of complication of DM, any disturbance in level of both zinc and copper have role in pathogenesis, prognosis of type 2 DM. This study aimed to assess the relationship between DM type 2 and trace elements by measured serum zinc and serum copper levels among Sudanese DM type 2 in Khartoum state.Materials and Methods: This is a descriptive, case control study, was conducted in Khartoum state, Sudan. During the period from April to July 2018. Forty Sudanese patients with DM (20 controlled patients with DM and 20 uncontrolled patients with DM) Diabetes patients were divided into controlled and uncontrolled groups by measuring HbA1C. (Female 25% and male 15%), with different age. were selected as case and 30 apparently healthy individuals were selected as control group. Serum zinc and copper levels were analysis using Atomic Absorption Spectroscopy and ichroma for HbA1c, the obtained results were analyzed using social science software package.Results: This study showed significant lower of serum zinc in diabetes type 2 patients comparison with control group and on another hand showed significant increase of serum copper in diabetes type 2 patients.We concluded serum zinc significant lower in both diabetes group than healthy group, copper significant high in both diabetes group than healthy group, gender have significant effect in serum zinc and copper, weak positive correlation between zinc and HbA1C and weak negative correlation between copper and HbA1C.Conclusion: This study concluded that the serum levels of Zinc significant lower in type 2 diabetes than healthy individuals. Serum levels of Copper significant increase in type 2 diabetes than healthy individuals as have been found in present study. Gender have significant effect in serum Zn and Cu in diabetic patients.Weak Positive correlation between serum Zinc with HbA1c and weak negative correlation between copper with HbA1c

2.
Article | IMSEAR | ID: sea-209640

ABSTRACT

Background:The gold standard for the diagnosis of Helicobacter pylori infection requires an endoscopic biopsy of gastric mucosa for histological examination, ureasetest and culture; however serological tests are useful as a screening test for Helicobacter pylori infection.Objective:To compare between Immunochromatographic Test and Enzyme Linked Immunosorbent Assay techniques in detection of Helicobacter pylori immunoglobulin gamma antibodiesin serum of patients suffer from gastritis.Materials and Methods:245 patients were screened for Helicobacter pylori infections by rapid urease test. Sera from these patients were tested for anti-Helicobacter pylori immunoglobulin gamma antibodiesby Enzyme Linked Immunosorbent Assay and Immunochromatographic Test techniques.Results:Of 245 patients tested, Immunochromatographic Test positive/negative 114 (46.5%)/131 (53.5%), whereas Enzyme Linked Immunosorbent Assay positive/negative were 124 (50.6%)/121 (49.4%). Sensitivity/ specificity was 67.4%/74.5% and 90.2%/89.3% for Immunochromatographic Test/Enzyme Linked Immunosorbent Assay positive/negative, respectively. The diagnostic accuracy was 71%/89.7% for Immunochromatographic Test/Enzyme Linked Immunosorbent Assay, respectively.Conclusion:The Enzyme Linked Immunosorbent Assay technique was found to be more sensitive, specific and accurate compared to the Immunochromatographic Test while The ImmunochromatographicTest is commercially available, inexpensive and easy to perform compared to the Enzyme Linked Immunosorbent Assay.

SELECTION OF CITATIONS
SEARCH DETAIL