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Chinese Journal of Surgery ; (12): 270-273, 2015.
Article in Chinese | WPRIM | ID: wpr-308558

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the clinical predictors of cytomegalovirus (CMV) infection after liver transplantation.</p><p><b>METHODS</b>The clinical data of 182 patients (146 male and 36 female with a mean age of (50 ± 7) years) receiving liver transplantation in Beijing Chaoyang Hospital between January 2004 and December 2008 were retrospectively analyzed.All patients were divided into two groups, namely the CMV infection group (n=24) and the control group (n=158). Logistic regression was used to identify the predictive factors of postoperative CMV infection.</p><p><b>RESULTS</b>According to univariate analysis results, the factors for CMV infection were acute liver failure (P=0.032), MELD score ≥ 30 (P=0.001), liver retransplantation (P=0.002), acute rejection (P=0.000) and delayed graft function (P=0.022). According to multi-analysis results, MELD score ≥ 30 (P=0.037, 95%CI:1.194-271.461) and acute rejection (P=0.033, 95%CI:1.179-51.863) were proved to be independent predictors by multivariate analysis.</p><p><b>CONCLUSION</b>The study indicates that MELD score ≥ 30 and acute rejection are the independent predictors of CMV infection.</p>


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Beijing , Cytomegalovirus Infections , Diagnosis , End Stage Liver Disease , Diagnosis , Graft Rejection , Liver Transplantation , Logistic Models , Multivariate Analysis , Postoperative Complications , Virology , Reoperation , Retrospective Studies , Severity of Illness Index
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