Apo-lipoproteins A-I and B and lipoprotein [A] in recent myocardial infarction with and without diabetes

In this study, the plasma lipids [total cholesterol [TC], low density lipoprotein cholesterol [LDLc], high density lipoprotein cholesterol [HDLc] and triglycerides]], apo A-1, apo B, Lp[a], TC/HDLc, LDLc/HDLc and apo B/apo A-1 ratios were measured in 120 males, aged 25-65 years, 40 normal controls and 80 patients with recent MI [45% of them had non-insulin-dependent diabetes mellitus]. Each group was divided into four subgroups according to age: Group 1 [>25-35 years], group 2 [>35-45 years], group 3 [>45- 55 years] and group 4 [55-65 years]. From the results obtained, it was concluded that lipid abnormalities might be considered an independent risk factor for development of MI. Apo-B, Lp[a] and the ratio apo-B/apo-A may be better predictors to the risk of atherosclerosis than other lipid abnormalities, especially when total cholesterol level is within normal Lp[a]

comparative study of lipoproteins, apolipoprotein A-I and B and lipoprotein [A] between Egyptian males and females in different age groups

Eighty normolipidemic healthy normal persons aged 25-65 years were chosen and divided into two groups, a male group [n=40] and a female group [n=40]. Each group was subdivided according to age into four subgroups: Group 1 [>25-35 years], group 2 [>35-45 years], group 3 [>45-55 years] and group 4 [>55-65 years]. For all cases, total cholesterol [TC], low-density lipoprotein [LDLc], high-density lipoprotein [HDLc], triglycerides [TG], apolipoproteins A-1 and B [Apo-A-1 and Apo-B] and lipoprotein [a] [Lp[a]] were measured. It was concluded that age and sex dependent reference normal range is important when assessing atherosclerotic risk by lipoprotein assay and it must be followed, better for each community separately