Mean anti-Mullerian hormone levels; comparison in fertile and infertile women of reproductive age

To compare the means of Anti-Mullerian hormone levels in both fertile and infertile women.Case-Control study. This study was conducted at infertility clinic of Gynecology and Obstetrics Unit-II, Civil Hospital, Karachi. The total duration of the study was approximately 1 year from October 2011 to October 2012. A total of 52 infertile women attending the Gynae-Unit-II out-patient clinic at Civil Hospital, Karachi and 48 fertile non-pregnant females of reproductive age group i.e. 20-35 years who met the inclusion criteria were included in the study. The serum Anti-Mullerian hormone levels were measured in both the infertile and fertile groups. Blood samples to determine AntiMullerian hormone levels were obtained irrespective of their menstrual cycle days. Independent sample t-test showed decreased mean serum Anti-Mullerian hormone levels in infertile group [cases] than the fertile controls. Mean concentration of serum AntiMullerian hormone in infertile women was significantly lower than that in fertile control women

Visfatin and its relationship with the severity of coronary artery disease in Pakistani population

To determine plasma visfatin in patients with and without coronary artery disease and to correlate it with the coronary vessels blockage by using anagiography. Comparative Cross Sectional Study. This study was conducted at the Department of Biochemistry, Ziauddin University and Jinnah Medical and Dental College, Karachi from June 2009 to November 2010. The study includes 80 subjects [mean age 48.8 +/- 6.15; 40-55 years age range] who underwent coronary angiography for suspected coronary artery disease. Plasma visfatin levels were determined by using ELISA. Out of these 80 study subjects, 30 [37.5%] had single vessel CAD, 12 [15%] had two vessels CAD, 24 [30%] had three vessels CAD and 14 [17.5%] had non significant disease. Serum Visfatin levels were higher in three vessel disease [5.82 +/- 0.58] when compared with non significant [4.55 +/- 1.10] single vessel disease [4.86 +/- 0.93] and two vessels disease [5.53 +/- 0.79] respectively but these values were statistically nonsignificant in all four study groups. Serum Visfatin levels were high in all three study groups when compared with non significant disease group and positive correlation of serum visfatin with the extent of the coronary artery disease was observed